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Inversin 抗体 (AA 31-130) (Alexa Fluor 350)

INVS 适用: 人, 小鼠 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 350
产品编号 ABIN1693617
发货至: 中国
  • 抗原 See all Inversin (INVS) 抗体
    Inversin (INVS)
    抗原表位
    • 14
    • 5
    • 1
    • 1
    AA 31-130
    适用
    • 22
    • 15
    • 1
    人, 小鼠
    宿主
    • 21
    • 1
    克隆类型
    • 22
    多克隆
    标记
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Inversin antibody is conjugated to Alexa Fluor 350
    应用范围
    • 18
    • 12
    • 12
    • 9
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠
    预测反应
    Rat,Cow,Sheep,Chimpanzee
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Inversin
    亚型
    IgG
    Top Product
    Discover our top product INVS Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Inversin (INVS)
    别名
    Inversin (INVS 产品)
    别名
    invs-a antibody, INVS antibody, MGC140477 antibody, inv antibody, NPH2 antibody, NPHP2 antibody, INV antibody, Nphp2 antibody, RGD1563359 antibody, wu:fe47e11 antibody, inversin S homeolog antibody, inversin antibody, Inversin antibody, invs.S antibody, INVS antibody, Bm1_38710 antibody, PTRG_09181 antibody, EAMY_RS33690 antibody, LOAG_11716 antibody, invs antibody, Invs antibody
    背景

    Synonyms: INV, Inversion of embryo turning homolog, inversion of embryonic turning, INVS, Nephrocystin 2, Nephrocystin-2, Nephrocystin2, nephronophthisis 2 infantile, NPH2, NPHP2, INVS_HUMAN.

    Background: Nephrocystin-2 is a 1,065 amino acid protein that exists as three alternatively spliced isoforms and is essential for establishment of the left-right axis and normal renal development. Localizing to the cytoplasm, cytoskeleton, membrane and nucleus, nephrocystin-2 is expressed during presomite-stage embryos and persists in adulthood, with high levels of expression in liver and kidney. Mice expressing nephrocystin-2 mutations are primarily generated by random insertional mutagenesis and result in the reversal of left/right polarity and cyst formation in the kidneys. Furthermore, altered nephrocystin-2 function reverses nodal and lefty expression, indicating that nephrocystin-2 signaling occurs upstream of these proteins involved in the development of asymmetry.

    基因ID
    27130
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