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PPP2R4 抗体 (AA 1-323)

PPP2R4 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1682265
发货至: 中国
  • 抗原 See all PPP2R4 抗体
    PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))
    抗原表位
    • 8
    • 8
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-323
    适用
    • 57
    • 27
    • 21
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 50
    • 7
    • 1
    克隆类型
    • 46
    • 12
    多克隆
    标记
    • 33
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This PPP2R4 antibody is un-conjugated
    应用范围
    • 36
    • 17
    • 13
    • 9
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF)
    序列
    MAEGERQPPP DSSEEAPPAT QNFIIPKKEI HTVPDMGKWK RSQAYADYIG FILTLNEGVK GKKLTFEYRV SEAIEKLVAL LNTLDRWIDE TPPVDQPSRF GNKAYRTWYA KLDEEAENLV ATVVPTHLAA AVPEVAVYLK ESVGNSTRID YGTGHEAAFA AFLCCLCKIG VLRVDDQIAI VFKVFNRYLE VMRKLQKTYR MEPAGSQGVW GLDDFQFLPF IWGSSQLIDH PYLEPRHFVD EKAVNENHKD YMFLECILFI TEMKTGPFAE HSNQLWNISA VPSWSKVNQG LIRMYKAECL EKFPVIQHFK FGSLLPIHPV TSG
    交叉反应
    人, 小鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of human Ser/thr-PP2A activator (PTPA) (NP_821067.1).
    亚型
    IgG
    Top Product
    Discover our top product PPP2R4 Primary Antibody
  • 应用备注
    IF,1:50 - 1:200
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • Jiang, Cao, Wang, Li, Liu, Lv, Li, Mi: "Cysteine transporter SLC3A1 promotes breast cancer tumorigenesis." in: Theranostics, Vol. 7, Issue 4, pp. 1036-1046, (2017) (PubMed).

    Wang, Gan, Wang, Wu, Cao, Zhu, Xu, Wang, Han, Li, Ye, Zhao, Mi: "Cancer-associated Fibroblasts Promote Irradiated Cancer Cell Recovery Through Autophagy." in: EBioMedicine, Vol. 17, pp. 45-56, (2017) (PubMed).

  • 抗原
    PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))
    别名
    PPP2R4 (PPP2R4 产品)
    背景
    Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.,PTPA,PP2A,PPP2R4,PR53,Signal Transduction,PI3K-Akt Signaling Pathway,Cell Biology & Developmental Biology,TGF-b-Smad Signaling Pathway,ESC Pluripotency and Differentiation,PPP2R4
    分子量
    31 kDa/33 kDa/36 kDa/40 kDa
    基因ID
    5524
    UniProt
    Q15257
    途径
    PI3K-Akt Signaling, M Phase, Hepatitis C, Toll-Like Receptors Cascades
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