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RAP1GAP 抗体

RAP1GAP 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN1680949
发货至: 中国
  • 抗原 See all RAP1GAP 抗体
    RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))
    适用
    • 31
    • 15
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    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 22
    • 10
    克隆类型
    • 20
    • 12
    单克隆
    标记
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This RAP1GAP antibody is un-conjugated
    应用范围
    • 18
    • 9
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human Rap1GAP
    亚型
    IgG
    Top Product
    Discover our top product RAP1GAP Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    限制
    仅限研究用
  • 缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))
    别名
    RAP1GAP (RAP1GAP 产品)
    别名
    RAP1GA1 antibody, RAP1GAP1 antibody, RAP1GAPII antibody, RAPGAP antibody, 1300019I11Rik antibody, 2310004O14Rik antibody, AI427470 antibody, Rap1ga1 antibody, RAP1 antibody, RAP1GAP antibody, rap1ga1 antibody, rap1gap1 antibody, rap1gapii antibody, rapgap antibody, zgc:175180 antibody, DKFZp459A114 antibody, RAP1 GTPase activating protein antibody, Rap1 GTPase-activating protein antibody, RAP1 GTPase activating protein 1 antibody, RAP1 GTPase activating protein L homeolog antibody, Rap1 GTPase-activating protein 1 antibody, si:dkey-166d12.2 antibody, RAP1GAP antibody, Rap1gap antibody, RAP1GAP1 antibody, rap1gap.L antibody, Tsp_09520 antibody, rap1gap antibody, si:dkey-166d12.2 antibody
    背景
    This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Aug 2011],RAP1GA1, RAP1GAP1, RAP1GAPII, RAPGAP,Cancer,Epigenetics & Nuclear Signaling,Signal Transduction,Tumor suppressors,RAP1GAP
    分子量
    95 kDa
    基因ID
    5909
    UniProt
    P47736
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