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FAM193B 抗体 (N-Term)

FAM193B 适用: 人 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1587943
发货至: 中国
  • 抗原 See all FAM193B products
    FAM193B (Family with Sequence Similarity 193, Member B (FAM193B))
    抗原表位
    • 3
    • 1
    N-Term
    适用
    宿主
    • 3
    克隆类型
    • 3
    多克隆
    标记
    • 3
    This FAM193B antibody is un-conjugated
    应用范围
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), ELISA
    特异性
    At least two isoforms of FAM193B are known to exist, this antibody will detect both isoforms.
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    FAM193B antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human FAM193B.
    亚型
    IgG
  • 应用备注
    FAM193B antibody can be used for detection of FAM193B by Western blot at 1 μg/mL. For immunofluorescence start at 20 μg/mL.
    说明

    (NT) Family with sequence similarity 193 member B

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
    储存条件
    4 °C
    储存方法
    FAM193B antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
    有效期
    12 months
  • 抗原
    FAM193B (Family with Sequence Similarity 193, Member B (FAM193B))
    别名
    FAM193B (FAM193B 产品)
    别名
    IRIZIO antibody, Kiaa1931 antibody, family with sequence similarity 193 member B antibody, family with sequence similarity 193, member B antibody, FAM193B antibody, Fam193b antibody
    背景
    FAM193B, also known as IRIZIO, was initially identified as a protein that is upregulated in alveolar rhabdomyosarcoma (ARMS), a type of fast-growing tumor characterized by chromosomal translocations fusing the PAX3 or PAX7 gene with that of FOXO1. It has been suggested that, in addition to the PAX3-FOXO1 gene fusion, disruption of the Rb and p53 pathways is required for full ARMS tumorigenesis. In PAX3-FOXO1-expressing primary mouse fibroblasts that possessed a defective p53 pathway, FAM193B expression enabled the tumorigenic transformation, suggesting that FAM193B may contribute to rhabdomyosarcomagenesis in humans.
    分子量
    99 kDa
    基因ID
    54540
    UniProt
    Q96PV7
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