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PABPC4 抗体 (AA 219-247)

PABPC4 适用: 人 WB 宿主: 兔 Polyclonal RB37035 unconjugated
产品编号 ABIN1538105
发货至: 中国
  • 抗原 See all PABPC4 抗体
    PABPC4 (Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4))
    抗原表位
    • 7
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 219-247
    适用
    • 36
    • 14
    • 14
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 35
    • 1
    克隆类型
    • 36
    多克隆
    标记
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PABPC4 antibody is un-conjugated
    应用范围
    • 29
    • 17
    • 11
    • 7
    • 5
    • 3
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This PABPC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 219-247 amino acids from the Central region of human PABPC4.
    克隆位点
    RB37035
    亚型
    Ig Fraction
    Top Product
    Discover our top product PABPC4 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    PABPC4 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    有效期
    6 months
  • 抗原
    PABPC4 (Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4))
    别名
    PABPC4 (PABPC4 产品)
    别名
    cb12 antibody, sb:cb12 antibody, PABP antibody, ePAB antibody, ePABP antibody, APP-1 antibody, APP1 antibody, PABP4 antibody, iPABP antibody, polyadenylate-binding protein 4 antibody, poly(A) binding protein, cytoplasmic 4 antibody, poly(A) binding protein, cytoplasmic 4 (inducible form) antibody, poly(A) binding protein cytoplasmic 4 L homeolog antibody, poly(A) binding protein cytoplasmic 4 antibody, Bm1_06880 antibody, Pabpc4 antibody, pabpc4 antibody, pabpc4.L antibody, PABPC4 antibody
    背景
    Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    分子量
    70783
    基因ID
    8761
    NCBI登录号
    NP_001129125, NP_001129126, NP_003810
    UniProt
    Q13310
    途径
    SARS-CoV-2 Protein Interactome
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