CLP1 抗体 (C-Term)
Quick Overview for CLP1 抗体 (C-Term) (ABIN1537107)
抗原
See all CLP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 308-336, C-Term
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预测反应
- B, C, Pr, M, Rat
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This CLP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-336 amino acids from the C-terminal region of human CLP1.
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亚型
- Ig Fraction
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anti-Cleavage and Polyadenylation Factor I Subunit 1 (CLP1) (Center) antibody
CLP1 适用: 人 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Factor I Subunit 1 (CLP1) (AA 316-425) antibodyCLP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8D5 unconjugated
anti-Cleavage and Polyadenylation Factor I Subunit 1 (CLP1) (AA 316-425) antibodyCLP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Factor I Subunit 1 (CLP1) (AA 1-425) antibodyCLP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Factor I Subunit 1 (CLP1) (AA 1-425) antibodyCLP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- CLP1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
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有效期
- 6 months
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- CLP1 (Cleavage and Polyadenylation Factor I Subunit 1 (CLP1))
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别名
- CLP1
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背景
- Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing, this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.
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分子量
- 47646
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基因ID
- 10978
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NCBI登录号
- NP_001136069, NP_006822
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UniProt
- Q92989
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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