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- 抗原 See all POLR1A 抗体
- POLR1A (Polymerase (RNA) I Polypeptide A, 194kDa (POLR1A))
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抗原表位
- AA 1437-1465, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This POLR1A antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This POLR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1437-1465 amino acids from the C-terminal region of human POLR1A.
- 克隆位点
- RB39202
- 亚型
- Ig Fraction
- Top Product
- Discover our top product POLR1A Primary Antibody
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- POLR1A Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
- 有效期
- 6 months
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- 抗原
- POLR1A (Polymerase (RNA) I Polypeptide A, 194kDa (POLR1A))
- 别名
- POLR1A (POLR1A 产品)
- 别名
- 194kDa antibody, 3010014K16Rik antibody, RPA194 antibody, Rpo1-4 antibody, mRPA1 antibody, Rpa1 antibody, A190 antibody, RPA1 antibody, RPO1-4 antibody, RPO14 antibody, polymerase (RNA) I polypeptide A antibody, RNA polymerase I subunit A antibody, Polr1a antibody, POLR1A antibody
- 背景
- DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol I. A bridging helix emanates from RPA1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol I by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition (By similarity).
- 分子量
- 194811
- 基因ID
- 25885
- NCBI登录号
- NP_056240
- UniProt
- O95602
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