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IL-6 抗体 (AA 30-212)

Name: IL-6 抗体 (AA 30-212)
Brand: antibodies-online
SKU: ABIN1513075
Availability: OutOfStock

IL6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of extracts of Rat lung, using IL6 antibody (ABIN1513075, ABIN1514222, ABIN1683697 and ABIN6213773) at 1:1000 dilution.

Western Blotting (WB) image for anti-Interleukin 6 (IL6) (AA 30-212) antibody (ABIN1513075)

(A) Immunohistochemical staining for TNF-α, IL-1β, and IL-6 in colon tissues of different groups.

IHC

3 images

(4 references)

产品编号 ABIN1513075

发货至: 中国

Datasheet as PDF

抗原 See all IL-6 (IL6) 抗体

IL-6 (IL6) (Interleukin 6 (IL6))
抗原表位
19

17

15

15

15

15

8

8

7

7

7

5

5

5

5

4

4

3

3

1

1

1

1

1

1

1

1

1
AA 30-212
适用
170

129

69

28

22

21

15

13

7

6

4

3

3

3

2
人
宿主
195

82

54

11

4

3

2
兔
Compatible Secondaries
克隆类型
213

135

1
多克隆
标记
190

57

26

10

9

8

4

4

4

4

4

4

3

3

3

3

3

2

2

2

1

1

1

1

1

1

1
This IL-6 antibody is un-conjugated
应用范围
262

132

104

52

50

46

41

41

38

30

25

25

22

20

15

8

7

6

6

5

3

2

2

1

1

1

1

1

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

序列

VPPGEDSKDV AAPHRQPLTS SERIDKQIRY ILDGISALRK ETCNKSNMCE SSKEALAENN LNLPKMAEKD GCFQSGFNEE TCLVKIITGL LEFEVYLEYL QNRFESSEEQ ARAVQMSTKV LIQFLQKKAK NLDAITTPDP TTNASLLTKL QAQNQWLQDM TTHLILRSFK EFLQSSLRAL RQM

交叉反应

人, 小鼠, 大鼠

产品特性

Polyclonal Antibodies

纯化方法

Affinity purification

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 30-212 of human IL6 (NP_000591.1).

亚型

IgG

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IL6 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated

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IL6 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 6 (IL6) (AA 26-50) antibody
IL6 适用: 人, 大鼠 ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

WB,1:500 - 1:2000,IHC,1:50 - 1:200

限制

仅限研究用
状态

Liquid

缓冲液

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid freeze / thaw cycles

储存条件

-20 °C

储存方法

Store at -20°C. Avoid freeze / thaw cycles.
Qin, Yang, Huang, Du, Mai, Xiao, Lü: "Sulforaphane attenuates microglia-mediated neuronal necroptosis through down-regulation of MAPK/NF-κB signaling pathways in LPS-activated BV-2 microglia." in: Pharmacological research, Vol. 133, pp. 218-235, (2018) (PubMed).

Chen, Yu, Yuan, Zhang, Fan, Yuan, Zhang, Yao: "Enriched housing promotes post-stroke functional recovery through astrocytic HMGB1-IL-6-mediated angiogenesis." in: Cell death discovery, Vol. 3, pp. 17054, (2017) (PubMed).

Meng, Zhang, Shi, Zhang, Yuan: "Inhibition of interleukin-6 abolishes the promoting effects of pair housing on post-stroke neurogenesis." in: Neuroscience, Vol. 307, pp. 160-70, (2016) (PubMed).

Liu, Lu, Zhou, Xu, Chen: "Flexible gold electrode array for multiplexed immunoelectrochemical measurement of three protein biomarkers for prostate cancer." in: ACS applied materials & interfaces, Vol. 6, Issue 22, pp. 20137-43, (2014) (PubMed).
抗原

IL-6 (IL6) (Interleukin 6 (IL6))

别名

IL6 (IL6 产品)

别名

BSF2 antibody, HGF antibody, HSF antibody, IFNB2 antibody, IL-6 antibody, Il-6 antibody, ILg6 antibody, Ifnb2 antibody, il6 antibody, CHIL-6 antibody, interleukin 6 antibody, interleukin-6 antibody, IL6 antibody, Il6 antibody, il-6 antibody, IL-6 antibody

背景

This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants.,IL6,BSF-2,BSF2,CDF,HGF,HSF,IFN-beta-2,IFNB2,IL-6,Cancer,Tumor immunology,Invasion and Metastasis,Cell Biology & Developmental Biology,Apoptosis,Growth factor,Endocrine & Metabolism,Endocrine and metabolic diseases,Metabolic disorders,Obesity,Immunology & Inflammation,Cytokines,Interleukins,IL-6 Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Neurodegenerative Diseases Markers,Other Neurological disorders,Cardiovascular,Angiogenesis,Angiogenic growth factors,IL6

分子量

23 kDa

基因ID

3569

UniProt

P05231

途径

TLR signaling, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome