SPINK7/ECRG2 抗体 (C-Term)
SPINK7
适用: 人, 小鼠, 大鼠
WB, IHC (p), EIA
宿主: 小鸡
Polyclonal
unconjugated
-
- 抗原 See all SPINK7/ECRG2 (SPINK7) 抗体
- SPINK7/ECRG2 (SPINK7) (Serine Peptidase Inhibitor, Kazal Type 7 (SPINK7))
-
抗原表位
- C-Term
-
适用
- 人, 小鼠, 大鼠
-
宿主
-
小鸡
-
克隆类型
- 多克隆
-
标记
- This SPINK7/ECRG2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 16 amino acid synthetic peptide near the carboxy terminus of Human ECRG2
- Top Product
- Discover our top product SPINK7 Primary Antibody
-
anti-Serine Peptidase Inhibitor, Kazal Type 7 (SPINK7) (AA 51-85) antibody
SPINK7 适用: 人, 小鼠 ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Serine Peptidase Inhibitor, Kazal Type 7 (SPINK7) antibodySPINK7 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- 抗原
- SPINK7/ECRG2 (SPINK7) (Serine Peptidase Inhibitor, Kazal Type 7 (SPINK7))
- 别名
- ECRG-2 (SPINK7 产品)
- 别名
- Ecg2 antibody, Ecrg2 antibody, OM antibody, ECG2 antibody, ECRG2 antibody, EG408198 antibody, serine peptidase inhibitor, Kazal type 7 antibody, serine peptidase inhibitor, Kazal type 7 (putative) antibody, Spink7 antibody, SPIK7 antibody, SPINK7 antibody
- 背景
- The esophageal cancer-susceptibility gene 2 (ECRG2), also known as SPINK7, is a novel tumor suppressor gene identified from the human esophagus. It interacts directly with metallothionein 2A and urokinase-type plasminogen activator (uPA), and downregulates the activity of uPA, leading to reduced cancer cell migration, invasion and metastasis. ECRG2 forms a complex with uPA and its receptor uPAR, modifying the dynamic association of uPAR with beta1 integrins and disrupting the Src/MAP kinase pathway that normally stimulates cell migration and invasion. ECRG2 may thus represent a novel therapeutic target for cancer.Synonyms: ECG2, Esophagus cancer-related gene 2 protein, MGC133105, MGC133106, SPINK7, Serine protease inhibitor Kazal-type 7, UNQ745/PRO1474
- 基因ID
- 84651
-
You are here:
