-
- 抗原 See all CD46 抗体
- CD46
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This CD46 antibody is un-conjugated
-
应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- 纯化方法
- Protein A agarose
- 免疫原
- Human pancreatic carcinoma cell line (AsPC1)
- 克隆位点
- TGP3
- 亚型
- IgG2a
- Top Product
- Discover our top product CD46 Primary Antibody
-
anti-CD46 (CD46) (AA 40-320) antibody
CD46 适用: 人 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD46 (CD46) (AA 35-179) antibodyCD46 适用: 人 WB, FACS, ELISA, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 1A5A5 unconjugated
anti-CD46 (CD46) (AA 317-343) antibodyCD46 适用: 人 WB, FACS, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD46 (CD46) (AA 251-355) antibodyCD46 适用: 人, 小鼠 WB, FACS, ELISA, IHC (p), ICC, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-CD46 (CD46) antibodyCD46 适用: 人, Cow WB, FACS, IP 宿主: 小鼠 Monoclonal MEM-258 unconjugated
anti-CD46 (CD46) antibodyCD46 适用: 人, Cow WB, FACS, IP 宿主: 小鼠 Monoclonal MEM-258 unconjugated
anti-CD46 (CD46) antibodyCD46 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 7D12 unconjugated Recombinant Antibody
anti-CD46 (CD46) antibody (FITC)CD46 适用: 人, Cow FACS 宿主: 小鼠 Monoclonal MEM-258 FITC
anti-CD46 (CD46) antibody (Biotin)CD46 适用: 人, Cow WB, FACS, IP 宿主: 小鼠 Monoclonal MEM-258 Biotin
anti-CD46 (CD46) antibody (APC)CD46 适用: 人, Cow FACS 宿主: 小鼠 Monoclonal MEM-258 APC
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
- 储存液
- Without preservative
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Upon receipt, store (in aliqouts) at -20 °C.
-
- 抗原
- CD46
- 别名
- CD46 / MCP (CD46 产品)
- 别名
- AHUS2 antibody, MCP antibody, MIC10 antibody, TLX antibody, TRA2.10 antibody, Mcp antibody, CD46 antibody, CD46 molecule antibody, CD46 antigen, complement regulatory protein antibody, CD46 molecule, complement regulatory protein antibody, membrane cofactor protein-like antibody, CD46 antibody, Cd46 antibody, LOC100341359 antibody, LOC103789310 antibody
- 背景
- CD46, also known as membrane cofactor protein (MCP), was first described as a membrane complement regulator that fu nctions as a cofactor with factor I to cleave complement factors C3b and C4b and thereby protect the cell from co mplement attack. In humans, CD46 is expressed on all nuc leated cells. In the rodent animals, its expression is limited only in testis, indicating that the major function of CD46 among different species lies in fertilization. CD46 and other membrane complement regulatory proteins (CD55 and CD59) are frequently overexpressed on cancer cells, possibly as a mechanism for cancer cells to overcome lysis by complement. Several pathogens, including viruses and bacteria (measles virus, human herpesvirus 6, human group B and D adenoviruses, Streptococcus pyogenes , and pathogenic Neisseria species) have been reported to use CD46 for invasion. Recent evidence also indicates that CD 46 signaling events play an important role in linking innate and acquired immune function.Synonyms: MIC10, Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen
- 基因ID
- 9606
- UniProt
- P15529
- 途径
- Regulation of Actin Filament Polymerization
-
You are here:
