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PKD1L3 抗体 (AA 121-220) (Cy7)

PKD1L3 适用: 人 IF (cc), IF (p) 宿主: 兔 Polyclonal Cy7
产品编号 ABIN1410258
发货至: 中国
  • 抗原 See all PKD1L3 抗体
    PKD1L3 (Polycystic Kidney Disease 1 Like 3 (PKD1L3))
    抗原表位
    • 14
    • 5
    AA 121-220
    适用
    宿主
    • 19
    克隆类型
    • 19
    多克隆
    标记
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PKD1L3 antibody is conjugated to Cy7
    应用范围
    • 12
    • 12
    • 7
    • 3
    • 3
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human PKD1L3
    亚型
    IgG
    Top Product
    Discover our top product PKD1L3 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    PKD1L3 (Polycystic Kidney Disease 1 Like 3 (PKD1L3))
    别名
    PKD1L3 (PKD1L3 产品)
    别名
    polycystic kidney disease 1 like 3 antibody, polycystin 1 like 3, transient receptor potential channel interacting antibody, Pkd1l3 antibody, PKD1L3 antibody
    背景

    Synonyms: PC1 like 3 protein, Polycystic kidney disease 1 like 3, Polycystic kidney disease protein 1 like 3, Polycystin 1 like 3, Polycystin 1L3,PK1L3_HUMAN.

    Background: Polycystin-1L3 is a 1,732 amino acid multi-pass membrane protein that contains one PLAT domain, one GPS domain and one C-type lectin domain. Expressed at high levels in placenta and present at lower levels in lung and heart, Polycystin-1L3 is thought to function as an ion-channel regulator that may interact with Polycystin-L and play a role in heteromeric taste channels. The gene encoding Polycystin-1L3 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

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