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TOR1B 抗体 (AA 281-336) (HRP)

TOR1B 适用: 小鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal HRP
产品编号 ABIN1409474
发货至: 中国
  • 抗原 See all TOR1B 抗体
    TOR1B (Torsin Family 1, Member B (Torsin B) (TOR1B))
    抗原表位
    • 14
    • 9
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 1
    • 1
    • 1
    AA 281-336
    适用
    • 32
    • 25
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 47
    克隆类型
    • 47
    多克隆
    标记
    • 14
    • 5
    • 5
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TOR1B antibody is conjugated to HRP
    应用范围
    • 47
    • 27
    • 15
    • 13
    • 13
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    小鼠
    预测反应
    Human,Rat,Dog,Cow,Sheep,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Torsin B
    亚型
    IgG
    Top Product
    Discover our top product TOR1B Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    TOR1B (Torsin Family 1, Member B (Torsin B) (TOR1B))
    Abstract
    TOR1B 产品
    背景

    Synonyms: DQ1, Tor1b, Torsin 1B, TOR1B, FKSG18, Torsin family 1 member B, TOR1B_HUMAN.

    Background: TorsinB is a 336 amino acid protein that localizes to the lumen of endoplasmic reticulum and belongs to the Torsin family. Expressed in a variety of tissues with particularly high levels in adult brain, TorsinB is thought to function as a molecular chaperone that assists in the conformational folding of membrane and secreted proteins. Via its ability to regulate protein folding, TorsinB plays a key role in postnatal developmental events and is essential for proper neurological development. TorsinB contains two PKC (protein kinase C) phosphorylations sites, one ATP binding domain and several conserved cysteines and shares 69 % amino acid identity with TorsinA, a related family member. Defects in the gene encoding TorsinB are associated with torsion dystonia, an autosomal dominant neurological disorder that is characterized by debilitating muscle contractions throughout the body.

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