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MARCH9 抗体 (Alexa Fluor 488)

MARCH9 适用: 人, 小鼠, 大鼠 WB, IF (p) 宿主: 兔 Polyclonal Alexa Fluor 488
产品编号 ABIN1402174
发货至: 中国
  • 抗原 See all MARCH9 抗体
    MARCH9 (Membrane-Associated Ring Finger (C3HC4) 9 (MARCH9))
    适用
    • 41
    • 24
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    人, 小鼠, 大鼠
    宿主
    • 38
    • 2
    克隆类型
    • 39
    • 2
    多克隆
    标记
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    This MARCH9 antibody is conjugated to Alexa Fluor 488
    应用范围
    • 40
    • 16
    • 12
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human MARCH9
    亚型
    IgG
    Top Product
    Discover our top product MARCH9 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    MARCH9 (Membrane-Associated Ring Finger (C3HC4) 9 (MARCH9))
    别名
    MARCH9 (MARCH9 产品)
    别名
    Rnf179 antibody, March-IX antibody, MARCH-IX antibody, RNF179 antibody, AI608492 antibody, BC019560 antibody, membrane associated ring-CH-type finger 9 antibody, membrane associated ring-CH-type finger 9 S homeolog antibody, membrane-associated ring finger (C3HC4) 9 antibody, March9 antibody, march9.S antibody, MARCH9 antibody, march9 antibody
    背景

    Synonyms: E3 ubiquitin protein ligase MARCH9, MARCH IX, Membrane associated RING CH protein IX, membrane associated ring finger C3HC4 9, Membrane associated RING finger protein 9, RING finger protein 179, RNF179, MARH9_HUMAN.

    Background: Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). MARCH9 (membrane-associated ring finger (C3HC4) 9), also known as RNF179, is a 346 amino acid multi-pass membrane protein that localizes to the golgi apparatus and contains one RING-CH-type zinc finger. Expressed ubiquitously, MARCH9 exists as a homodimer and functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and is thought to promote the degradation of target proteins, such as CD4 and MHC-I. Multiple isoforms of MARCH9 exist due to alternative splicing events.

    基因ID
    92979
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