SERPINB3 + SERPINB4 抗体 (Alexa Fluor 488)
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- 抗原
- SERPINB3 + SERPINB4
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- Alexa Fluor 488
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human SERPINB3 (same as SERPINB4)
- 亚型
- IgG
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-
- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
-
- 抗原
- SERPINB3 + SERPINB4
- 别名
- HsT1196 antibody, SCC antibody, SCCA-1 antibody, SCCA-PD antibody, SCCA1 antibody, T4-A antibody, serpin family B member 3 antibody, SERPINB3 antibody
- 背景
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Synonyms: HsT1196, Protein T4 A, Protein T4-A, SCC, SCCA PD, SCCA-1, SCCA1, SCCAPD, Serine or cysteine proteinase inhibitor clade B ovalbumin member 3, Serpin B3, Serpin peptidase inhibitor clade B ovalbumin member 3, SERPINB3, SPB3_HUMAN, Squamous cell carcinoma antigen 1, T4 A, T4A, SCCA 2, SCCA2, Leupin, Peptidase inhibitor 11, PI 11, PI-11, PI11, Protease inhibitor leucine serpin, SCCA-2, SCCA1, SCCA2/SCCA1 fusion protein, Serine or cysteine proteinase inhibitor, clade B ovalbumin, member 4, Serpin B4, Serpin peptidase inhibitor, clade B ovalbumin, member 4, SERPINB 4, SERPINB4, SPB4_HUMAN, Squamous cell carcinoma antigen 1, Squamous cell carcinoma antigen 2.
Background: Metastasis of a primary tumor to a distant site is determined through signaling cascades that break down interactions between the cell and extracellular matrix proteins. Among the proteins mediating metastasis are serine prote-ases, such as neutrophil elastase.SCCA is transcribed by two nearly identical genes (SCCA1 and SCCA2), and is mainly produced as SCCA1. The human SCCA1 gene encodes a 390 amino acid protein that was originally isolated from a metastatic cervical squamous cell carcinoma. SCCA2 may act as a protease inhibitor to modulate the host immune response against tumor cells.
- 基因ID
- 6317
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