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ERN1 抗体 (AA 252-260) (FITC)

ERN1 适用: 人, 小鼠, 大鼠, Pig WB, FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal FITC
产品编号 ABIN1400144
发货至: 中国
  • 抗原 See all ERN1 抗体
    ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))
    抗原表位
    • 16
    • 15
    • 15
    • 13
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 252-260
    适用
    • 102
    • 77
    • 73
    • 15
    • 1
    人, 小鼠, 大鼠, Pig
    宿主
    • 106
    • 4
    • 3
    • 1
    克隆类型
    • 107
    • 7
    多克隆
    标记
    • 33
    • 11
    • 9
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    This ERN1 antibody is conjugated to FITC
    应用范围
    • 81
    • 44
    • 28
    • 25
    • 25
    • 10
    • 9
    • 7
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, Pig, 大鼠
    预测反应
    Dog,Cow,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human IRE1a
    亚型
    IgG
    Top Product
    Discover our top product ERN1 Primary Antibody
  • 应用备注
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • Li, Han, Shi: "IRE1?-XBP1 Pathway Is Activated Upon Induction of Single-Prolonged Stress in Rat Neurons of the Medial Prefrontal Cortex." in: Journal of molecular neuroscience : MN, (2015) (PubMed).

  • 抗原
    ERN1 (Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1))
    别名
    IRE1a (ERN1 产品)
    别名
    IRE1 antibody, IRE1P antibody, IRE1a antibody, hIRE1p antibody, 9030414B18Rik antibody, AI225830 antibody, C85377 antibody, Ire1a antibody, Ire1alpha antibody, Ire1p antibody, RGD1559716 antibody, Ern1 antibody, Ire1 antibody, Ire1b antibody, sb:eu1005 antibody, zgc:109932 antibody, endoplasmic reticulum to nucleus signaling 1 antibody, endoplasmic reticulum to nucleus signaling 2 antibody, endoplasmic reticulum (ER) to nucleus signalling 1 antibody, serine/threonine-protein kinase/endoribonuclease IRE1 antibody, endoplasmic reticulum (ER) to nucleus signalling 2 antibody, ERN1 antibody, ERN2 antibody, Ern1 antibody, LOC524719 antibody, Ern2 antibody, ern1 antibody
    背景

    Synonyms: IRE1, IRE1P, IRE1a, hIRE1p, Serine/threonine-protein kinase/endoribonuclease IRE1, Endoplasmic reticulum-to-nucleus signaling 1, Inositol-requiring protein 1, Ire1-alpha, ERN1

    Background: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.

    基因ID
    2081
    UniProt
    O75460
    途径
    ER-Nucleus Signaling, Unfolded Protein Response
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