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MMS19 抗体 (AA 851-950) (Alexa Fluor 488)

MMS19 适用: 人, 小鼠 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 488
产品编号 ABIN1400098
发货至: 中国
  • 抗原 See all MMS19 抗体
    MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))
    抗原表位
    • 14
    • 7
    • 1
    • 1
    • 1
    • 1
    AA 851-950
    适用
    • 29
    • 17
    • 3
    人, 小鼠
    宿主
    • 25
    • 4
    克隆类型
    • 27
    • 2
    多克隆
    标记
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MMS19 antibody is conjugated to Alexa Fluor 488
    应用范围
    • 29
    • 13
    • 12
    • 12
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠
    预测反应
    Rat,Dog,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human MMS 19
    亚型
    IgG
    Top Product
    Discover our top product MMS19 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))
    别名
    MMS19 (MMS19 产品)
    别名
    MET18 antibody, MMS19L antibody, hMMS19 antibody, 2410001K24Rik antibody, 2610042O15Rik antibody, AI316855 antibody, C79368 antibody, C86341 antibody, Mms19l antibody, mms19 antibody, mms19l antibody, MMS19 homolog, cytosolic iron-sulfur assembly component antibody, MMS19 (MET18 S. cerevisiae) antibody, MMS19 homolog, cytosolic iron-sulfur assembly component L homeolog antibody, MMS19 antibody, Mms19 antibody, mms19.L antibody
    背景

    Synonyms: MET18, MMS19L, hMMS19, MMS19 nucleotide excision repair protein homolog, MET18 homolog, MMS19-like protein, MMS19

    Background: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.

    基因ID
    64210
    UniProt
    Q96T76
    途径
    Nuclear Hormone Receptor Binding
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