GDAP1 抗体 (AA 151-230) (Alexa Fluor 555)
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- 抗原 See all GDAP1 抗体
- GDAP1 (Ganglioside-Induced Differentiation-Associated Protein 1 (GDAP1))
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抗原表位
- AA 151-230
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GDAP1 antibody is conjugated to Alexa Fluor 555
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human GDAP1
- 亚型
- IgG
- Top Product
- Discover our top product GDAP1 Primary Antibody
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anti-Ganglioside-Induced Differentiation-Associated Protein 1 (GDAP1) antibody
GDAP1 适用: 小鼠, 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ganglioside-Induced Differentiation-Associated Protein 1 (GDAP1) (AA 158-257) antibodyGDAP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ganglioside-Induced Differentiation-Associated Protein 1 (GDAP1) (AA 1-225) antibodyGDAP1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- GDAP1 (Ganglioside-Induced Differentiation-Associated Protein 1 (GDAP1))
- 别名
- GDAP1 (GDAP1 产品)
- 别名
- CMT4 antibody, CMT4A antibody, CMTRIA antibody, ganglioside induced differentiation associated protein 1 antibody, ganglioside-induced differentiation-associated-protein 1 antibody, GDAP1 antibody, Gdap1 antibody
- 背景
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Synonyms: Ganglioside induced dferentiation associated protein 1, Ganglioside-induced dferentiation-associated protein 1, GDAP1, GDAP1_HUMAN.
Background: Glutathione S-transferases (GSTs) function to conjugate reduced glutathione to many exogenous and endogenous hydrophobic electrophiles. Although it shares the carboxy and amino-terminal glutathione S-transferase domains, GDAP1 is characterized as a GST-like protein because it contains an extended GST domain II and a predicted transmembrane domain, two characteristics which are unusual for GST family members. GDAP1 may function in a signal transduction pathway that is responsible for ganglioside-induced neurite differentiation and also may play a role in protecting myelin membranes from free-radical damage. Mutations in the gene encoding GDAP1 is the cause of many forms of Charcot-Marie-Tooth disease, a common inherited disorder of the peripheral nervous system that is characterized by reduced nerve conduction velocities, slow progressive distal muscle atrophy and absent deep tendon reflexes.
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