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SERPINE2 抗体 (AA 301-398)

SERPINE2 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387740
发货至: 中国
  • 抗原 See all SERPINE2 抗体
    SERPINE2 (serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 (SERPINE2))
    抗原表位
    • 14
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-398
    适用
    • 50
    • 23
    • 20
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 34
    • 17
    • 2
    • 2
    • 1
    克隆类型
    • 40
    • 16
    多克隆
    标记
    • 28
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SERPINE2 antibody is un-conjugated
    应用范围
    • 47
    • 25
    • 19
    • 12
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human GDN/SERPINE2
    亚型
    IgG
    Top Product
    Discover our top product SERPINE2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    SERPINE2 (serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 (SERPINE2))
    别名
    GDN (SERPINE2 产品)
    别名
    GDN antibody, GDNPF antibody, PI-7 antibody, PI7 antibody, PN-1 antibody, PN1 antibody, PNI antibody, SERPINE2 antibody, MGC143011 antibody, Gdnpn1 antibody, Pn-1 antibody, Spin4 antibody, B230326M24Rik antibody, PAI-1 antibody, Spi4 antibody, zgc:55929 antibody, serpin family E member 2 antibody, serine (or cysteine) peptidase inhibitor, clade E, member 2 antibody, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 antibody, SERPINE2 antibody, serpine2 antibody, Serpine2 antibody
    背景

    Synonyms: Glia derived nexin, Protease inhibitor 7, GDN, GDN_HUMAN, Glia-derived nexin, P17 antibody Peptidase inhibitor 7, Pi-7, Plasminogen activator inhibitor type 1, member 2, PN-1, PN1, PNI, Protease nexin 1, Protease nexin I, Serpin E2, Serpin peptidase inhibitor, clade E nexin, plasminogen activator inhibitor type 1, member 2, SERPINE 2, Serpine2.

    Background: The serine protease inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, including the control of blood coagulation, complement activation, programmed cell death and development. Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. Protease nexin-1 (PN-1) is a serpin that inactivates several proteases, including thrombin, urokinase, plasminogen activators (PA) and plasmin. It is involved in tissue remodeling, cellular invasiveness, matrix degradation and tumor growth. PN-1 expression is abundant in the nervous system, where it inhibits thrombin, thereby playing a role in neural injury and repair processes. An imbalance between PN-1 and thrombin may be a contributing factor in the pathology of Alzheimer??s disease.

    基因ID
    5270
    UniProt
    P07093
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