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IL28RA 抗体 (AA 51-150)

IL28RA 适用: 人 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387718
发货至: 中国
  • 抗原 See all IL28RA 抗体
    IL28RA (Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA))
    抗原表位
    • 15
    • 12
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 51-150
    适用
    • 41
    • 10
    • 8
    • 7
    • 7
    • 5
    • 4
    • 4
    • 4
    • 2
    • 1
    宿主
    • 44
    • 1
    • 1
    克隆类型
    • 46
    多克隆
    标记
    • 14
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL28RA antibody is un-conjugated
    应用范围
    • 41
    • 22
    • 12
    • 12
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    特异性
    Predicted to also work in Rat based on sequence similarity
    交叉反应
    预测反应
    Mouse,Rat,Dog,Cow,Pig,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human IL-28R
    亚型
    IgG
    Top Product
    Discover our top product IL28RA Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • McGuire, Frieling, Lo, Li, Muhammad, Lawrence, Lawrence, Cook, Lynch: "Mesenchymal stem cell-derived interleukin-28 drives the selection of apoptosis resistant bone metastatic prostate cancer." in: Nature communications, Vol. 12, Issue 1, pp. 723, (2021) (PubMed).

  • 抗原
    IL28RA (Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA))
    别名
    IL-28R (IL28RA 产品)
    别名
    IFNLR1 antibody, IL28RA antibody, crf2/12 antibody, ifnlr antibody, il-28r1 antibody, il28ra antibody, licr2 antibody, ifnlr1 antibody, CRF2-12 antibody, Il28ra antibody, CRF2/12 antibody, IFNLR antibody, IL-28R1 antibody, LICR2 antibody, RGD1562689 antibody, interferon lambda receptor 1 antibody, interferon, lambda receptor 1 antibody, interferon, lambda receptor 1 L homeolog antibody, IFNLR1 antibody, ifnlr1 antibody, ifnlr1.L antibody, Ifnlr1 antibody
    背景

    Synonyms: IFNLR, LICR2, IL28RA, CRF2/12, IL-28R1, Interferon lambda receptor 1, IFN-lambda receptor 1, IFN-lambda-R1, Cytokine receptor class-II member 12, Cytokine receptor family 2 member 12, CRF2-12, Interleukin-28 receptor subunit alpha, IL-28 receptor subunit alpha, IL-28R-alpha, IL-28RA, Likely interleukin or cytokine receptor 2, IFNLR1

    Background: The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. Determines the cell type specificity of the lambda interferon action. Shows a more restricted pattern of expression in the epithelial tissues thereby limiting responses to lambda interferons primarily to epithelial cells of the respiratory, gastrointestinal, and reproductive tracts. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium.

    基因ID
    163702
    UniProt
    Q8IU57
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