WWC1 抗体 (AA 351-450)
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- 抗原 See all WWC1 抗体
- WWC1 (WW and C2 Domain Containing 1 (WWC1))
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抗原表位
- AA 351-450
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This WWC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Dog,Cow,Sheep,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human KIBRA
- 亚型
- IgG
- Top Product
- Discover our top product WWC1 Primary Antibody
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anti-WW and C2 Domain Containing 1 (WWC1) (AA 847-1094) antibody
WWC1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-WW and C2 Domain Containing 1 (WWC1) (AA 950-1050) antibodyWWC1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-WW and C2 Domain Containing 1 (WWC1) antibodyWWC1 适用: 人 WB 宿主: 小鼠 Monoclonal 1B1 unconjugated
anti-WW and C2 Domain Containing 1 (WWC1) antibodyWWC1 适用: 人 WB 宿主: 小鼠 Monoclonal 1H8 unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- WWC1 (WW and C2 Domain Containing 1 (WWC1))
- 别名
- KIBRA (WWC1 产品)
- 背景
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Synonyms: KIBRA, HBEBP3, HBEBP36, MEMRYQTL, PPP1R168, Protein KIBRA, HBeAg-binding protein 3, Kidney and brain protein, WW domain-containing protein 1, WWC1, KIAA0869
Background: Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of the ERK/MAPK cascade. Modulates directional migration of podocytes. Acts as a substrate for PRKCZ. Plays a role in cognition and memory performance.
- 基因ID
- 23286
- UniProt
- Q8IX03
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