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SLC51B 抗体 (AA 1-35)

OSTBETA 适用: 小鼠 ELISA, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1386750
发货至: 中国
  • 抗原 See all SLC51B (OSTBETA) 抗体
    SLC51B (OSTBETA) (Organic Solute Transporter beta (OSTBETA))
    抗原表位
    • 5
    • 2
    AA 1-35
    适用
    • 23
    • 19
    • 17
    小鼠
    宿主
    • 25
    克隆类型
    • 25
    多克隆
    标记
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC51B antibody is un-conjugated
    应用范围
    • 20
    • 6
    • 3
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    小鼠
    预测反应
    Human,Rat
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human OST-beta
    亚型
    IgG
    Top Product
    Discover our top product OSTBETA Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Stipanuk, Jurkowska, Niewiadomski, Mazor, Roman, Hirschberger: "Identification of Taurine-Responsive Genes in Murine Liver Using the Cdo1-Null Mouse Model." in: Advances in experimental medicine and biology, Vol. 975, pp. 475-495, (2017) (PubMed).

  • 抗原
    SLC51B (OSTBETA) (Organic Solute Transporter beta (OSTBETA))
    别名
    OST-beta (OSTBETA 产品)
    别名
    Ostb antibody, Ostbeta antibody, RGD1565748 antibody, OSTB antibody, OSTBETA antibody, solute carrier family 51, beta subunit antibody, solute carrier family 51 beta subunit antibody, Slc51b antibody, SLC51B antibody
    背景

    Synonyms: organic solute transporter beta Ostbeta, Organic solute transporter subunit beta, Ostbeta, Ost beta, OST-beta, OSTB, OSTB_HUMAN.

    Background: The heteromeric transporter OST Alpha/OST Beta facilitates the transport of bile and other steroid solutes across the basolateral epithelial cell membrane of intestine, liver, testis, kidney and adrenal gland. OST Alpha/OST Beta expression is induced by bile acids through ligand-dependent transactivation of their genes by FXR (Farnesoid X-activated receptor). This genetic regulation suggests that in response to changes in intracellular bile acid levels, bile acids adjust the rate of their own efflux from enterocytes. OST Beta is a 128 amino acid single-pass transmembrane protein that requires OST Alpha to localize to the plasma membrane. Coexpression of OST Alpha and OST Beta is also required to convert the OST Alpha subunit to a mature glycosylated endoglycosidase H-resistant form, suggesting that co-expression facilitates trafficking of OST Alpha through the golgi apparatus. Though widely expressed, OST Beta is present at highest levels in ileum.

    基因ID
    123264
    途径
    Regulation of Carbohydrate Metabolic Process
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