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TNF alpha 抗体

TNF alpha 适用: 人 ELISA, IHC, Func, ELISpot 宿主: 小鼠 Monoclonal B-C7 unconjugated
产品编号 ABIN1383955
发货至: 中国
  • 抗原 See all TNF alpha 抗体
    TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This TNF alpha antibody is un-conjugated
    应用范围
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    ELISA, Immunohistochemistry (IHC), Functional Studies (Func), ELISpot
    特异性
    Recognises both natural and recombinant human TNF-a
    纯化方法
    Ion exchange chromatography
    过滤
    0.22 μm filtered
    免疫原
    Recombinant human TNF-a,Myeloma X63/AG.8653 x Balb/c spleen cells
    克隆位点
    B-C7
    亚型
    IgG1 kappa
    Biological Activity Comment
    Inhibits TNFα induced cytotoxicity on U937 cells
    Top Product
    Discover our top product TNF alpha Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free
    储存液
    Without preservative
    储存条件
    4 °C
    储存方法
    Store at +2-8°C for 12 months. DO NOT FREEZE.
  • Arduise, Abache, Li, Billard, Chabanon, Ludwig, Mauduit, Boucheix, Rubinstein, Le Naour: "Tetraspanins regulate ADAM10-mediated cleavage of TNF-alpha and epidermal growth factor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 10, pp. 7002-13, (2008) (PubMed).

    Venet, Pachot, Debard, Bohe, Bienvenu, Lepape, Powell, Monneret: "Human CD4+CD25+ regulatory T lymphocytes inhibit lipopolysaccharide-induced monocyte survival through a Fas/Fas ligand-dependent mechanism." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 177, Issue 9, pp. 6540-7, (2006) (PubMed).

    Dyugovskaya, Lavie, Lavie: "Phenotypic and functional characterization of blood gammadelta T cells in sleep apnea." in: American journal of respiratory and critical care medicine, Vol. 168, Issue 2, pp. 242-9, (2003) (PubMed).

    Limb, Daniels, Pleass, Charteris, Luthert, Khaw: "Differential expression of matrix metalloproteinases 2 and 9 by glial Müller cells: response to soluble and extracellular matrix-bound tumor necrosis factor-alpha." in: The American journal of pathology, Vol. 160, Issue 5, pp. 1847-55, (2002) (PubMed).

    Hamacher, Lucas, Lijnen, Buschke, Dunant, Wendel, Grau, Suter, Ricou: "Tumor necrosis factor-alpha and angiostatin are mediators of endothelial cytotoxicity in bronchoalveolar lavages of patients with acute respiratory distress syndrome." in: American journal of respiratory and critical care medicine, Vol. 166, Issue 5, pp. 651-6, (2002) (PubMed).

    Musey, Ding, Cao, Lee, Galloway, Yuen, Jerome, McElrath: "Ontogeny and specificities of mucosal and blood human immunodeficiency virus type 1-specific CD8(+) cytotoxic T lymphocytes." in: Journal of virology, Vol. 77, Issue 1, pp. 291-300, (2002) (PubMed).

    Marfaing-Koka, Maravic, Humbert, Galanaud, Emilie: "Contrasting effects of IL-4, IL-10 and corticosteroids on RANTES production by human monocytes." in: International immunology, Vol. 8, Issue 10, pp. 1587-94, (1997) (PubMed).

    Voorzanger, Touitou, Garcia, Delecluse, Rousset, Joab, Favrot, Blay: "Interleukin (IL)-10 and IL-6 are produced in vivo by non-Hodgkin's lymphoma cells and act as cooperative growth factors." in: Cancer research, Vol. 56, Issue 23, pp. 5499-505, (1997) (PubMed).

    Mey, Hmama, Normier, Revillard: "Alteration of dealcylated lipopolysaccharide antagonistic properties by interaction with plasma factors." in: Journal of leukocyte biology, Vol. 61, Issue 1, pp. 17-23, (1997) (PubMed).

    Ida, Robertson, Voss, Ritz, Anderson: "CD94 ligation induces apoptosis in a subset of IL-2-stimulated NK cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 159, Issue 5, pp. 2154-60, (1997) (PubMed).

    van Hensbroek, Palmer, Onyiorah, Schneider, Jaffar, Dolan, Memming, Frenkel, Enwere, Bennett, Kwiatkowski, Greenwood: "The effect of a monoclonal antibody to tumor necrosis factor on survival from childhood cerebral malaria." in: The Journal of infectious diseases, Vol. 174, Issue 5, pp. 1091-7, (1996) (PubMed).

    Racadot, Milpied, Bordigoni, Cahn, Plouvier, Lioure, Lutz, Wijdenes, Herve: "Sequential use of three monoclonal antibodies in corticosteroid-resistant acute GVHD: a multicentric pilot study including 15 patients." in: Bone marrow transplantation, Vol. 15, Issue 5, pp. 669-77, (1995) (PubMed).

    Boillot, Capellier, Racadot, Wijdenes, Herve, Barale: "Pilot clinical trial of an anti-TNF alpha monoclonal antibody for the treatment of septic shock." in: Clinical intensive care : international journal of critical & coronary care medicine, Vol. 6, Issue 2, pp. 52-6, (1995) (PubMed).

    Hervé, Flesch, Tiberghien, Wijdenes, Racadot, Bordigoni, Plouvier, Stephan, Bourdeau, Holler: "Phase I-II trial of a monoclonal anti-tumor necrosis factor alpha antibody for the treatment of refractory severe acute graft-versus-host disease." in: Blood, Vol. 79, Issue 12, pp. 3362-8, (1992) (PubMed).

    Hervé, Racadot, Wijdenes, Flesch, Tiberghien, Bordigoni, Holler, Powles, Bourdeau, Wilmer: "Monoclonal anti TNF alpha antibody in the treatment of acute GvHD refractory both to corticosteroids and anti IL-2 R antibody." in: Bone marrow transplantation, Vol. 7 Suppl 2, pp. 149, (1991) (PubMed).

  • 抗原
    TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
    别名
    TNF alpha (TNF alpha 产品)
    别名
    DIF antibody, TNF-alpha antibody, TNFA antibody, TNFSF2 antibody, RATTNF antibody, Tnfa antibody, tnf antibody, TNF-a antibody, TNFalpha antibody, Tnfsf1a antibody, TNFa antibody, cTNF antibody, Tnf-alpha antibody, tnfa-like antibody, TNF-ALPHA antibody, dif antibody, tnfa antibody, xtnf antibody, tnfsf2 antibody, tnf-alpha antibody, Cachectin antibody, tumor necrosis factor antibody, tumor necrosis factor b (TNF superfamily, member 2) antibody, tumor necrosis factor alpha antibody, tumor necrosis factor a (TNF superfamily, member 2) antibody, TNF antibody, Tnf antibody, tnf antibody, tnfb antibody, tnf-alpha antibody, LOC103694380 antibody, tnfa antibody
    背景
    TNFa
    途径
    NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
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