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CD130/gp130 抗体

IL6ST 适用: 人 FACS, Func 宿主: 小鼠 Monoclonal B-K5 unconjugated
产品编号 ABIN1383681
发货至: 中国
  • 抗原 See all CD130/gp130 (IL6ST) 抗体
    CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
    适用
    • 138
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    宿主
    • 115
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    小鼠
    克隆类型
    • 117
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    单克隆
    标记
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    This CD130/gp130 antibody is un-conjugated
    应用范围
    • 97
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    Flow Cytometry (FACS), Functional Studies (Func)
    特异性
    Recognises Gp130, common subunit for IL-6, IL-11, OSM, LIF, CNTF, CT-1 receptors, a 130-140 kDa protein
    纯化方法
    Ion exchange chromatography
    过滤
    0.22 μm filtered
    免疫原
    Natural soluble gp130,Myeloma X63/AG.8653 x Balb/c spleen cells
    克隆位点
    B-K5
    亚型
    IgG1 kappa
    Biological Activity Comment
    Inhibits CNTF activity. Inhibits OSM binding to gp130
    Top Product
    Discover our top product IL6ST Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free
    储存液
    Without preservative
    储存条件
    4 °C
    储存方法
    Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
  • Durda, Dunn, Rose, Butera, Benson, Pandolfi, Kurnick: "Induction of \" in melanomas by oncostatin M: down-modulation of melanocyte antigen expression." in: Molecular cancer research : MCR, Vol. 1, Issue 6, pp. 411-9, (2003) (PubMed).

    Auguste, Guillet, Fourcin, Olivier, Veziers, Pouplard-Barthelaix, Gascan: "Signaling of type II oncostatin M receptor." in: The Journal of biological chemistry, Vol. 272, Issue 25, pp. 15760-4, (1997) (PubMed).

    Gu, Wijdenes, Zhang, Hallet, Clement, Klein: "Anti-gp130 transducer monoclonal antibodies specifically inhibiting ciliary neurotrophic factor, interleukin-6, interleukin-11, leukemia inhibitory factor or oncostatin M." in: Journal of immunological methods, Vol. 190, Issue 1, pp. 21-7, (1996) (PubMed).

    Chevalier, Fourcin, Robledo, Wijdenes, Pouplard-Barthelaix, Gascan: "Interleukin-6 family of cytokines induced activation of different functional sites expressed by gp130 transducing protein." in: The Journal of biological chemistry, Vol. 271, Issue 25, pp. 14764-72, (1996) (PubMed).

    Baumann, Morella, White, Dembski, Bailon, Kim, Lai, Tartaglia: "The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 16, pp. 8374-8, (1996) (PubMed).

  • 抗原
    CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
    别名
    CD130 (IL6ST 产品)
    别名
    CD130 antibody, CDW130 antibody, GP130 antibody, IL-6RB antibody, 5133400A03Rik antibody, AA389424 antibody, BB405851 antibody, D13Ertd699e antibody, gp130 antibody, Ac1055 antibody, Gp130 antibody, Il-6rb antibody, IL-6 antibody, interleukin 6 signal transducer antibody, IL6ST antibody, Il6st antibody, il6st antibody
    背景
    Gp130
    分子量
    130-140 kDa
    途径
    JAK/STAT Signaling, Cellular Glucan Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Cancer Immune Checkpoints
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