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- 抗原 See all CD130/gp130 (IL6ST) 抗体
- CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD130/gp130 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Functional Studies (Func)
- 特异性
- Recognises Gp130, common subunit for IL-6, IL-11, OSM, LIF, CNTF, CT-1 receptors, a 130-140 kDa protein
- 纯化方法
- Ion exchange chromatography
- 过滤
- 0.22 μm filtered
- 免疫原
- Natural soluble gp130,Myeloma X63/AG.8653 x Balb/c spleen cells
- 克隆位点
- B-K5
- 亚型
- IgG1 kappa
- Biological Activity Comment
- Inhibits CNTF activity. Inhibits OSM binding to gp130
- Top Product
- Discover our top product IL6ST Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free
- 储存液
- Without preservative
- 储存条件
- 4 °C
- 储存方法
- Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
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Induction of \" in melanomas by oncostatin M: down-modulation of melanocyte antigen expression." in: Molecular cancer research : MCR, Vol. 1, Issue 6, pp. 411-9, (2003) (PubMed).
: "Signaling of type II oncostatin M receptor." in: The Journal of biological chemistry, Vol. 272, Issue 25, pp. 15760-4, (1997) (PubMed).
: "Anti-gp130 transducer monoclonal antibodies specifically inhibiting ciliary neurotrophic factor, interleukin-6, interleukin-11, leukemia inhibitory factor or oncostatin M." in: Journal of immunological methods, Vol. 190, Issue 1, pp. 21-7, (1996) (PubMed).
: "Interleukin-6 family of cytokines induced activation of different functional sites expressed by gp130 transducing protein." in: The Journal of biological chemistry, Vol. 271, Issue 25, pp. 14764-72, (1996) (PubMed).
: "The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 16, pp. 8374-8, (1996) (PubMed).
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Induction of \" in melanomas by oncostatin M: down-modulation of melanocyte antigen expression." in: Molecular cancer research : MCR, Vol. 1, Issue 6, pp. 411-9, (2003) (PubMed).
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- 抗原
- CD130/gp130 (IL6ST) (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
- 别名
- CD130 (IL6ST 产品)
- 别名
- CD130 antibody, CDW130 antibody, GP130 antibody, IL-6RB antibody, 5133400A03Rik antibody, AA389424 antibody, BB405851 antibody, D13Ertd699e antibody, gp130 antibody, Ac1055 antibody, Gp130 antibody, Il-6rb antibody, IL-6 antibody, interleukin 6 signal transducer antibody, IL6ST antibody, Il6st antibody, il6st antibody
- 背景
- Gp130
- 分子量
- 130-140 kDa
- 途径
- JAK/STAT Signaling, Cellular Glucan Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Cancer Immune Checkpoints
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