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TCR alpha/beta 抗体 (Biotin)

TCR alpha/beta 适用: 人 FACS 宿主: 小鼠 Monoclonal IP26 Biotin
产品编号 ABIN1302746
发货至: 中国
  • 抗原 See all TCR alpha/beta products
    TCR alpha/beta (T Cell Receptor alpha/beta (TCR alpha/beta))
    适用
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    宿主
    • 31
    • 16
    小鼠
    克隆类型
    • 47
    单克隆
    标记
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    This TCR alpha/beta antibody is conjugated to Biotin
    应用范围
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    Flow Cytometry (FACS)
    特异性
    The mouse monoclonal antibody IP26 recognizes a monomorphic extracellular determinant of TCR alpha/beta, the dominant subtype of T cell receptor expressed in human peripheral blood.
    交叉反应 (详细)
    Human
    纯化方法
    Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
    克隆位点
    IP26
    亚型
    IgG1
  • 应用备注
    Flow cytometry: Recommended dilution: 2-3 μg/mL, positive control: human peripheral blood T cells.
    说明

    The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.

    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    Avoid prolonged exposure to light.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Kuttruff, Koch, Kelp, Pawelec, Rammensee, Steinle: "NKp80 defines and stimulates a reactive subset of CD8 T cells." in: Blood, Vol. 113, Issue 2, pp. 358-69, (2009) (PubMed).

    Ortonne, Huet, Gaudez, Marie-Cardine, Schiavon, Bagot, Musette, Bensussan: "Significance of circulating T-cell clones in Sezary syndrome." in: Blood, Vol. 107, Issue 10, pp. 4030-8, (2006) (PubMed).

    Huet, Bagot, Loyaux, Capdevielle, Conraux, Ferrara, Bensussan, Marie-Cardine: "SC5 mAb represents a unique tool for the detection of extracellular vimentin as a specific marker of Sezary cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 1, pp. 652-9, (2005) (PubMed).

  • 抗原
    TCR alpha/beta (T Cell Receptor alpha/beta (TCR alpha/beta))
    别名
    TCR alpha/beta (TCR alpha/beta 产品)
    背景
    The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression.,TCRA/B
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