电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

IL3RA 抗体

IL3RA 适用: 人 WB, FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal 6H6 unconjugated
产品编号 ABIN1302506
发货至: 中国
  • 抗原 See all IL3RA 抗体
    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
    适用
    • 80
    • 26
    • 3
    宿主
    • 48
    • 35
    • 3
    • 1
    小鼠
    克隆类型
    • 45
    • 41
    • 1
    单克隆
    标记
    • 44
    • 8
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL3RA antibody is un-conjugated
    应用范围
    • 59
    • 49
    • 19
    • 15
    • 13
    • 13
    • 9
    • 9
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    The mouse monoclonal antibody 6H6 recognizes an extracellular epitope of CD123 (interleukin 3 receptor alpha), a 60-70 kDa transmembrane protein expressed by myeloid precursors, megakaryocytes, macrophages, dendritic cells, mast cells, basophils, and some B cells. This antibody does not inhibit IL-3 binding to its receptor.
    交叉反应 (详细)
    Human
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    IL3 receptor alpha chain expressed on the surface of transiently transfected COS cells
    克隆位点
    6H6
    亚型
    IgG1
    Top Product
    Discover our top product IL3RA Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • Martín-Gayo, Sierra-Filardi, Corbí, Toribio: "Plasmacytoid dendritic cells resident in human thymus drive natural Treg cell development." in: Blood, Vol. 115, Issue 26, pp. 5366-75, (2010) (PubMed).

    Herling, Teitell, Shen, Medeiros, Jones: "TCL1 expression in plasmacytoid dendritic cells (DC2s) and the related CD4+ CD56+ blastic tumors of skin." in: Blood, Vol. 101, Issue 12, pp. 5007-9, (2003) (PubMed).

  • 抗原
    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
    别名
    CD123 (IL3RA 产品)
    别名
    CD123 antibody, IL3R antibody, IL3RAY antibody, IL3RX antibody, IL3RY antibody, hIL-3Ra antibody, CDw123 antibody, SUT-1 antibody, Cyrl antibody, interleukin 3 receptor subunit alpha antibody, interleukin 3 receptor, alpha chain antibody, IL3RA antibody, Il3ra antibody
    背景
    Interleukin 3 receptor subunit alpha,CD123 is the alpha chain of interleukin 3 receptor (IL-3R alpha). This subunit heterodimerizes with the interleukin 3 receptor beta chain (CD131), which is shared with other receptors. CD123 interacts with IL-3 specifically, but with low affinity, and association with the beta subunit confers high affinity binding to the receptor heterodimer. Both chains are required for signaling, but receptor activation and signal transduction depend on IL-3 binding to CD123 as the initial step.,IL3RA, MGC34174, hIL-3Ra
    基因ID
    3563
    UniProt
    P26951
    途径
    JAK/STAT Signaling
You are here:
客服