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CCDC98 抗体 (AA 1-313)

FAM175A 适用: 人 WB, IP, FACS 宿主: 小鼠 Monoclonal ABRA1-01 unconjugated
产品编号 ABIN1302443
发货至: 中国
  • 抗原 See all CCDC98 (FAM175A) 抗体
    CCDC98 (FAM175A) (Family with Sequence Similarity 175, Member A (FAM175A))
    抗原表位
    • 15
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    AA 1-313
    适用
    • 25
    • 19
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 38
    • 3
    小鼠
    克隆类型
    • 37
    • 4
    单克隆
    标记
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCDC98 antibody is un-conjugated
    应用范围
    • 32
    • 13
    • 13
    • 13
    • 11
    • 9
    • 6
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS)
    特异性
    The mouse monoclonal antibody ABRA1-01 recognizes human ABRA1 (Abraxas, CCDC98), an adaptor protein involved in DNA repair, which migrates as a 45 kDa band on PAAGE under reducing conditions.
    交叉反应 (详细)
    Human, Other not tested
    纯化方法
    Purified by protein-A affinity chromatography.
    纯度
    > 95 % (by SDS-PAGE)
    免疫原
    Recombinant protein corresponding to amino acids 1-313 of ABRA1 with N-terminal His6 tag
    克隆位点
    ABRA1-01
    亚型
    IgG
    Top Product
    Discover our top product FAM175A Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 1-2 μg/mL. Intracellular staining.
    Western blotting: Reducing conditions.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    CCDC98 (FAM175A) (Family with Sequence Similarity 175, Member A (FAM175A))
    别名
    ABRA1 (FAM175A 产品)
    别名
    CCDC98 antibody, abra1 antibody, ccdc98 antibody, fam175a antibody, ABRA1 antibody, 3830405G04Rik antibody, 5630400M01Rik antibody, AI506069 antibody, AL024423 antibody, AV118690 antibody, Ccdc98 antibody, RGD1305287 antibody, zgc:103522 antibody, abraxas 1, BRCA1 A complex subunit antibody, Coiled-coil domain-containing protein 98 antibody, BRCA1 A complex subunit antibody, family with sequence similarity 175 member A antibody, abraxas 2a, BRISC complex subunit antibody, abraxas 1, BRCA1 A complex subunit S homeolog antibody, ABRAXAS1 antibody, abraxas1 antibody, Abraxas1 antibody, FAM175A antibody, abraxas2a antibody, abraxas1.S antibody
    背景
    Abraxas 1, BRCA1 A complex subunit,ABRA1 (Abraxas), also known as CCDC98, is an adaptor protein that is essential for formation and function of BRCA1 A tumor suppressor complex. This complex plays critical roles in DNA repair, cell cycle checkpoint control, and maintenance of genomic stability. ABRA1 mediates interaction of ubiquitin-interacting motif-containing protein RAP80 and deubiquitination enzyme BRCC36 with BRCA1/BARD1. ABRA1 controls both DNA-damage-induced formation of BRCA1 foci and BRCA1-dependent G2/M checkpoint activation.,ABRA1, Abraxas 1, CCDC98, FAM175A
    基因ID
    84142
    UniProt
    Q6UWZ7
    途径
    DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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