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- 抗原 See all ABCB6 抗体
- ABCB6 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6))
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抗原表位
- AA 440-455
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ABCB6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 犬
- 产品特性
- Concentration Definition: by UV absorbance at 280 nm
- 免疫原
- This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 440-455 of human ABCB6 protein.
- 亚型
- IgG
- Top Product
- Discover our top product ABCB6 Primary Antibody
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- 应用备注
- This affinity-purified antibody has been tested for use in ELISA and western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 94 kDa in size corresponding to ABCB6 protein by western blotting in the appropriate cell lysate or extract.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.0 mg/ml
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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Dormant cancer cells accumulate high protoporphyrin IX levels and are sensitive to 5-aminolevulinic acid-based photodynamic therapy." in: Scientific reports, Vol. 6, pp. 36478, (2016) (PubMed).
: "Conserved intramolecular disulfide bond is critical to trafficking and fate of ATP-binding cassette (ABC) transporters ABCB6 and sulfonylurea receptor 1 (SUR1)/ABCC8." in: The Journal of biological chemistry, Vol. 286, Issue 10, pp. 8481-92, (2011) (PubMed).
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Dormant cancer cells accumulate high protoporphyrin IX levels and are sensitive to 5-aminolevulinic acid-based photodynamic therapy." in: Scientific reports, Vol. 6, pp. 36478, (2016) (PubMed).
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- 抗原
- ABCB6 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6))
- 别名
- ABCB6 (ABCB6 产品)
- 别名
- ABCB6 antibody, abcb6 antibody, ABC antibody, ABC14 antibody, LAN antibody, MCOPCB7 antibody, MTABC3 antibody, PRP antibody, umat antibody, 1200005B17Rik antibody, ATP binding cassette subfamily B member 6 (Langereis blood group) antibody, ATP binding cassette subfamily B member 6 antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 6a antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 6 antibody, ABCB6 antibody, abcb6a antibody, abcb6 antibody, Abcb6 antibody
- 背景
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This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. ABCB6 (ATP-binding cassette sub-family B member 6, also known as mitochondrial precursor ABC transporter 3, Mt-ABC transporter 3, and ABC transporter umat) is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABCB6 is a membrane-associated protein that transports various molecules across the extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, DR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily confer multi-drug resistance (MDR) to cancer cells and are also involved in antigen presentation. ABCB6 also likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.
Synonyms: ABC antibody, ABC transporter umat antibody, ABC14 antibody, ATP binding cassette sub family B member 6, mitochondrial precursor antibody - 基因ID
- 10058, 13123949
- UniProt
- Q9NP58
- 途径
- Transition Metal Ion Homeostasis
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