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PTENP1 抗体 (pSer29, pThr32)

PTENP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN129639
发货至: 中国
  • 抗原 See all PTENP1 products
    PTENP1 (Phosphatase and Tensin Homolog Pseudogene 1 (PTENP1))
    抗原表位
    AA 223-237, pSer29, pThr32
    适用
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 2
    • 2
    克隆类型
    • 4
    多克隆
    标记
    • 4
    This PTENP1 antibody is un-conjugated
    应用范围
    • 4
    • 1
    • 1
    Western Blotting (WB), ELISA
    交叉反应
    小鼠, 绵羊, 犬, Macaque, Chimpanzee, 大鼠
    产品特性
    Concentration Definition: by UV absorbance at 280 nm
    免疫原
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to amino acids 223-237 of human PTEN-P1 protein.
    Immunogentype:Recombinant
    亚型
    IgG
  • 应用备注
    This affinity purified antibody has been tested for use in ELISA and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 41 kDa in size corresponding to PTEN-P1 protein by western blotting in the appropriate cell lysate or extract.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.87 mg/mL
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    PTENP1 (Phosphatase and Tensin Homolog Pseudogene 1 (PTENP1))
    别名
    PTEN-P1 (PTENP1 产品)
    别名
    PTEN-rs antibody, PTEN2 antibody, PTENpg1 antibody, PTH2 antibody, psiPTEN antibody, phosphatase and tensin homolog pseudogene 1 antibody, PTENP1 antibody
    背景
    This gene (PTENP1) is a highly homologous pseudogene of PTEN.  PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. PTEN is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tension like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.
    Synonyms: Phosphatase and tensin homolog pseudogene 1 antibody, psiPTEN antibody, PTEN rs antibody, PTEN2 antibody, PTH2 antibody, TEP1 antibody
    基因ID
    5728, 73765544
    UniProt
    Q43460
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