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Cyclin B1 抗体 (pSer126)

CCNB1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN129589
发货至: 中国
  • 抗原 See all Cyclin B1 (CCNB1) 抗体
    Cyclin B1 (CCNB1)
    抗原表位
    • 23
    • 23
    • 22
    • 16
    • 9
    • 8
    • 7
    • 7
    • 3
    • 3
    • 3
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 120-131, pSer126
    适用
    • 195
    • 92
    • 60
    • 20
    • 16
    • 15
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    宿主
    • 160
    • 42
    • 1
    克隆类型
    • 155
    • 48
    多克隆
    标记
    • 104
    • 10
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
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    • 4
    • 4
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    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Cyclin B1 antibody is un-conjugated
    应用范围
    • 133
    • 72
    • 56
    • 46
    • 40
    • 39
    • 39
    • 30
    • 25
    • 11
    • 11
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    Western Blotting (WB), ELISA
    交叉反应
    大鼠, 犬, Chimpanzee, 小鼠, Hamster
    产品特性
    Concentration Definition: by UV absorbance at 280 nm
    免疫原
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 120-131 of Human Cyclin B1 protein.
    亚型
    IgG
    Top Product
    Discover our top product CCNB1 Primary Antibody
  • 应用备注
    This affinity purified antibody has been tested for use in ELISA and western blot.   Specific conditions for reactivity should be optimized by the end user. Expect a band ~ 48 kDa in size corresponding to Cyclin B1 by western blotting in the appropriate cell lysate or extract.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2.01 mg/mL
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • Geng, Zhang, Zheng, Legerski: "Artemis links ATM to G2/M checkpoint recovery via regulation of Cdk1-cyclin B." in: Molecular and cellular biology, Vol. 27, Issue 7, pp. 2625-35, (2007) (PubMed).

  • 抗原
    Cyclin B1 (CCNB1)
    别名
    Cyclin B1 (CCNB1 产品)
    别名
    ccnb antibody, cycb antibody, cb267 antibody, cycb1 antibody, wu:fa19g04 antibody, wu:fb16d01 antibody, wu:fb16e07 antibody, wu:fi21c01 antibody, ccnb1 antibody, MGC53596 antibody, CCNB antibody, Ccnb1-rs1 antibody, Ccnb1-rs13 antibody, CycB1 antibody, Cycb-4 antibody, Cycb-5 antibody, Cycb1-rs1 antibody, cyclin B1 antibody, cyclin B1 S homeolog antibody, ccnb1 antibody, ccnb1.2 antibody, ccnb1.S antibody, CCNB1 antibody, Ccnb1 antibody, ccnb1.2.S antibody
    背景
    Cyclin B1 (also called CCNB1 and G2/mitotic-specific cyclin B1) is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form a serine/threonine kinase holoenzyme complex called the maturation-promoting factor (MPF). Two alternative transcripts have been found a constitutively expressed transcript and a cell cycle-regulated transcript that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.  S126 phosphorylation, the site of phosphorylation recognized by this antibody, is involved in an auto-phosphorylation of the cdk -cyclin complex.  Recognition of this phosphorylated site suggests the antibody is useful to detect the active form of the complex and may serve as a marker of mitosis.
    Synonyms: Cyclin B1, CCNB1, CCNB, G2/mitotic-specific cyclin-B1
    基因ID
    891
    UniProt
    P14635
    途径
    Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, M Phase
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