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ING3 抗体 (Isoform 1)

ING3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN129551
发货至: 中国
  • 抗原 See all ING3 抗体
    ING3 (Inhibitor of Growth Family, Member 3 (ING3))
    抗原表位
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 294-304, Isoform 1
    适用
    • 30
    • 19
    • 16
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 26
    • 4
    山羊
    克隆类型
    • 27
    • 3
    多克隆
    标记
    • 19
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ING3 antibody is un-conjugated
    应用范围
    • 18
    • 12
    • 9
    • 5
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    产品特性
    Concentration Definition: by UV absorbance at 280 nm
    免疫原
    This affinity purified antibody was prepared from whole Goat serum produced by repeated immunizations with a synthetic peptide corresponding aa 294-304 of Human ING3 protein (Inhibitor of growth family, member 3). This sequence only shows homology to for ING3.
    亚型
    IgG
    Top Product
    Discover our top product ING3 Primary Antibody
  • 应用备注
    This affinity purified antibody has been tested for use in ELISA against the immunizing peptide. Specific conditions for western blotting reactivity should be optimized by the end user.  Expect a band at approximately 47 kDa in size corresponding to ING3 isoform 1 by western blotting in the appropriate cell lysate or extract.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.10 mg/mL
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    ING3 (Inhibitor of Growth Family, Member 3 (ING3))
    别名
    p47 ING3 (ING3 产品)
    别名
    ING3 antibody, Eaf4 antibody, ING2 antibody, MEAF4 antibody, p47ING3 antibody, 1300013A07Rik antibody, P47ING3 antibody, zgc:56327 antibody, inhibitor of growth family member 3 antibody, inhibitor of growth family, member 3 antibody, inhibitor of growth protein 3 antibody, inhibitor of growth family member 3 L homeolog antibody, ING3 antibody, Ing3 antibody, CpipJ_CPIJ009396 antibody, ing3 antibody, ing3.L antibody
    背景
    P47 ING3 is a tumor suppressor protein similar to ING1 that  can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Over-expression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Multiple alternatively spliced transcript variants have been observed.  The accession number listed below is for variant (1) that encodes the longest isoform.
    Synonyms: Inhibitor of growth family member 3 antibody, Inhibitor of growth protein 3 antibody
    基因ID
    54556, 38201655
    UniProt
    Q9NXR8
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