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SMAD4 抗体

The 兔 多克隆 anti-SMAD4 antibody is suitable to detect SMAD4 in samples from 人, 小鼠 和 大鼠. It has been validated for WB.
产品编号 ABIN127142
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SMAD4 抗体 (ABIN127142)

抗原

See all SMAD4 抗体
SMAD4 (SMAD Family Member 4 (SMAD4))

适用

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人, 小鼠, 大鼠

宿主

  • 96
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克隆类型

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多克隆

标记

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This SMAD4 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 特异性

    The antibody recognizes ~70 kDa Smad4.

    纯化方法

    antigen affinity purified

    免疫原

    Synthetic peptide corresponding to amino acids residues around 281 of human Smad4.
  • 应用备注

    Western Blot: 1-4 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS containing 50 % glycerol, 1 % BSA, and 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C/-80 °C

    储存方法

    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • 抗原

    SMAD4 (SMAD Family Member 4 (SMAD4))

    别名

    SMAD4

    背景

    Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad), have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1, Smad5, and Smad8 are effectors of BMP2 and BMP4 function while Smad2 and Smad3 are involved in TGF-β and activin-mediated growth modulation. Smad4 has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members.Synonyms: DPC4, Deletion target in pancreatic carcinoma 4, MAD homolog 4, MADH4, Mothers against DPP homolog 4, Mothers against decapentaplegic homolog 4, SMAD 4, SMAD family member 4, SMAD-4

    基因ID

    4089

    NCBI登录号

    NP_005350

    UniProt

    Q13485

    途径

    Cell Division Cycle, Chromatin Binding, Autophagy
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