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NF-kB p65 抗体

NFkBP65 适用: 人, 小鼠, 大鼠 WB, IP, IHC (fro) 宿主: 小鼠 Monoclonal S8 (2A12A7) unconjugated
产品编号 ABIN126921
发货至: 中国
  • 抗原 See all NF-kB p65 (NFkBP65) 抗体
    NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 492
    • 42
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    小鼠
    克隆类型
    • 458
    • 82
    单克隆
    标记
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    This NF-kB p65 antibody is un-conjugated
    应用范围
    • 426
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    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody recognizes NFkB.
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse and Rat.
    产品特性
    Synonyms: NF kappa B p65, NFkB p65, Transcription factor p65, Rel A, NFKB3, Nuclear factorNF-kappa-B p65 subunit, Nuclear factor of kappa light polypeptide gene enhancer inB-cells 3
    纯化方法
    Affinity Chromatography.
    免疫原
    Synthetic peptide from Human NFkB. Remarks: Molecular Weight: 65 kDa
    克隆位点
    S8 (2A12A7)
    亚型
    IgG1
    Top Product
    Discover our top product NFkBP65 Primary Antibody
  • 应用备注
    Western Blot: 1-4 μg/mL. Immunoprecipitation. Immunohistochemistry. A431 cells can be used as a Positive Control.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    PBS containing 1 mg/mL BSA, 1.5 mM Sodium Azide and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C/-80 °C
    储存方法
    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))
    别名
    RELA / NF-kB p65 (NFkBP65 产品)
    别名
    C-Rel antibody, NFKB3 antibody, p65 antibody, NFkB antibody, c-rel antibody, zgc:100833 antibody, Xrel2 antibody, Xrel3 antibody, rel antibody, rel-A antibody, rel2 antibody, rel3 antibody, v-rel antibody, xrel antibody, REL proto-oncogene, NF-kB subunit antibody, RELA proto-oncogene, NF-kB subunit antibody, v-rel reticuloendotheliosis viral oncogene homolog A (avian) antibody, v-rel avian reticuloendotheliosis viral oncogene homolog antibody, v-rel avian reticuloendotheliosis viral oncogene homolog L homeolog antibody, REL antibody, RELA antibody, Rela antibody, Rel antibody, rel antibody, rel.L antibody
    背景
    NFkB was identified as a sequence specific transcriptional activator that binds to the intronic enhancer of kappa light chain gene in B lymphocytes. NFkB is a heterodimer that consists of a 50 kDa DNA binding subunit (p50) and a 65 kDa transactivation subunit (p65/RelA). Both of these subunits exhibit sequence homology to the protooncogene c-Rel. The p50/p65 heterodimer remains in the cytosol in an inactive form as a complex with its inhibitor, IkB. Upon stimulation of cells by a wide variety of stimuli such as lipopolysaccharide (LPS), proinflammatory cytokines, and viral infection. IkB is phosphorylated and degraded by proteosome. The active NFkB heterodimer is translocated into the nucleus and induces gene expression.Synonyms: NF kappa B p65, NFKB3, NFkB p65, Nuclear factor NF-kappa-B p65 subunit, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, Rel A, Transcription factor p65
    基因ID
    5970
    UniProt
    Q04206
    途径
    NF-kappaB Signaling, RTK signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades, S100 Proteins
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