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TCR gamma/delta 抗体

TCR gamma/delta 适用: 小鼠 FACS, IP, IHC (f) 宿主: Armenian Hamster Monoclonal UC7-13D5 unconjugated
产品编号 ABIN1177014
发货至: 中国
  • 抗原 See all TCR gamma/delta products
    TCR gamma/delta (T-Cell Receptor gamma/delta (TCR gamma/delta))
    适用
    • 23
    • 18
    • 8
    • 8
    • 5
    • 4
    小鼠
    宿主
    • 34
    • 12
    • 12
    • 2
    Armenian Hamster
    克隆类型
    • 60
    单克隆
    标记
    • 19
    • 13
    • 10
    • 8
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This TCR gamma/delta antibody is un-conjugated
    应用范围
    • 60
    • 17
    • 16
    • 11
    • 10
    • 3
    • 3
    • 2
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    品牌
    BD Pharmingen™
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    过滤
    0.2 μm filtered
    内毒素水平
    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
    免疫原
    Not Reported
    克隆位点
    UC7-13D5
    亚型
    IgG3 kappa
  • 限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
    储存液
    Azide free
    储存条件
    4 °C
    储存方法
    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • King, Hyde, Jackson, Novosad, Ellis, Putney, Stovall, Van Winkle, Beaman, Ferrick: "Cutting edge: protective response to pulmonary injury requires gamma delta T lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 9, pp. 5033-6, (1999) (PubMed).

    Shinohara, Ikarashi, Maruoka, Miyata, Sugimura, Terada, Wakasugi: "Functional and phenotypical characteristics of hepatic NK-like T cells in NK1.1-positive and -negative mouse strains." in: European journal of immunology, Vol. 29, Issue 6, pp. 1871-8, (1999) (PubMed).

    Tamaki, Yasaka, Chang, Ohtake, Saitoh, Nakamura, Furue: "Identification and characterization of novel dermal Thy-1 antigen-bearing dendritic cells in murine skin." in: The Journal of investigative dermatology, Vol. 106, Issue 3, pp. 571-5, (1996) (PubMed).

    van der Heyde, Elloso, Chang, Kaplan, Manning, Weidanz: "Gamma delta T cells function in cell-mediated immunity to acute blood-stage Plasmodium chabaudi adami malaria." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 8, pp. 3985-90, (1995) (PubMed).

    Kaufmann, Blum, Yamamoto: "Crosstalk between alpha/beta T cells and gamma/delta T cells in vivo: activation of alpha/beta T-cell responses after gamma/delta T-cell modulation with the monoclonal antibody GL3." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 20, pp. 9620-4, (1993) (PubMed).

    Skeen, Ziegler: "Induction of murine peritoneal gamma/delta T cells and their role in resistance to bacterial infection." in: The Journal of experimental medicine, Vol. 178, Issue 3, pp. 971-84, (1993) (PubMed).

    Hiromatsu, Yoshikai, Matsuzaki, Ohga, Muramori, Matsumoto, Bluestone, Nomoto: "A protective role of gamma/delta T cells in primary infection with Listeria monocytogenes in mice." in: The Journal of experimental medicine, Vol. 175, Issue 1, pp. 49-56, (1992) (PubMed).

    Bluestone, Cron, Barrett, Houlden, Sperling, Dent, Hedrick, Rellahan, Matis: "Repertoire development and ligand specificity of murine TCR gamma delta cells." in: Immunological reviews, Vol. 120, pp. 5-33, (1991) (PubMed).

    Lefrancois: "Phenotypic complexity of intraepithelial lymphocytes of the small intestine." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 147, Issue 6, pp. 1746-51, (1991) (PubMed).

    MacDonald, Schreyer, Howe, Bron: "Selective expression of CD8 alpha (Ly-2) subunit on activated thymic gamma/delta cells." in: European journal of immunology, Vol. 20, Issue 4, pp. 927-30, (1990) (PubMed).

    Tigelaar, Lewis, Bergstresser: "TCR gamma/delta+ dendritic epidermal T cells as constituents of skin-associated lymphoid tissue." in: The Journal of investigative dermatology, Vol. 94, Issue 6 Suppl, pp. 58S-63S, (1990) (PubMed).

  • 抗原
    TCR gamma/delta (T-Cell Receptor gamma/delta (TCR gamma/delta))
    别名
    gamma delta TCR (TCR gamma/delta 产品)
    背景
    The UC7-13D5 antibody reacts with the gammadelta T-cell Receptor (TCR) complex on gammadelta TCR-expressing T lymphocytes and NK-T cells of all mouse strains tested. It does not react with the alphabeta TCR-bearing T cells. In the mouse, cell expressing the gammadelta TCR are found in the thymus, intestinal epithelium, epidermis, dermis, pulmonary epithelium, peritoneum, liver, and peripheral lymphoid organs. Plate-bound UC7-13D5 antibody activates gammadelta TCR-bearing T cells, and in vivo administration of the mAb depletes peripheral gammadelta TCR-bearing T cells.
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