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F4/80 抗体 (PE)

EMR1 适用: 小鼠 FACS, IF 宿主: 大鼠 Monoclonal CI:A3-1 PE
产品编号 ABIN111857
发货至: 中国
  • 抗原 See all F4/80 (EMR1) 抗体
    F4/80 (EMR1) (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1))
    适用
    • 91
    • 52
    • 30
    • 4
    • 4
    • 1
    小鼠
    宿主
    • 54
    • 47
    • 4
    • 3
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    • 1
    大鼠
    克隆类型
    • 54
    • 49
    • 2
    单克隆
    标记
    • 43
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    • 8
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    This F4/80 antibody is conjugated to PE
    应用范围
    • 79
    • 56
    • 25
    • 17
    • 13
    • 12
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    Flow Cytometry (FACS), Immunofluorescence (IF)
    特异性
    This antibody recognises the F4/80 antigen. Clone CI:A3-1 has been reported to modulate cytokine levels released in response to Listeria monocytogenes (5). We recommende the use of Cat.-No BM4008LE for this purpose.
    交叉反应 (详细)
    Species reactivity (tested):Mouse.
    纯化方法
    Affinity Chromatography on Protein A
    免疫原
    Thioglycollate stimulated peritoneal cavity macrophages from C57/BL mice. Remarks: Spleen cells from immunised HOB2 rats were fused with cells of the mouse NS-1 mouse myeloma cell line.
    克隆位点
    CI:A3-1
    亚型
    IgG2b
    Top Product
    Discover our top product EMR1 Primary Antibody
  • 应用备注
    Flow Cytometry: use 10 μL of neat antibody to label 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore with 1 mL distilled water.
    缓冲液
    PBS, pH 7.4, 0.09 % Sodium Azide, 1 % BSA, 5 % Sucrose
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    This product is photosensitive and should be protected from light
    储存条件
    4 °C
    储存方法
    Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
  • 抗原
    F4/80 (EMR1) (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 1 (EMR1))
    别名
    Macrophage F4/80 Antigen (EMR1 产品)
    别名
    EMR1 antibody, TM7LN3 antibody, DD7A5-7 antibody, EGF-TM7 antibody, F4/80 antibody, Gpf480 antibody, Ly71 antibody, adhesion G protein-coupled receptor E1 antibody, ADGRE1 antibody, LOC100424335 antibody, Adgre1 antibody
    背景
    Murine F4/80 antigen is a 160 kD cell surface glycoprotein that is a member of the EGF-TM7 family of proteins which shares 68 % overall amino acid identity with Human EGF module-containing mucin-like hormone receptor 1 (EMR1). Expression of F4/80 is heterogeneous and is reported to vary during macrophage maturation and activation. The F4/80 antigen is expressed on a wide range of mature tissue macrophages including Kupffer cells, Langerhans, microglia, macrophages located in the gut lamina propria, peritoneal cavity, lung, thymus, bone marrow stroma and macrophages in the red pulp of the spleen. F4/80 expression has also been reported on a subpopulation of dendritic cells but is absent from macrophages located in T cell areas of the spleen and lymph node. The ligands and biological functions of the F4/80 antigen have not yet been determined but recent studies suggest a role for F4/80 in the generation of efferent CD8+ve regulatory T cells.Synonyms: Cell surface glycoprotein EMR1, EMR1 hormone receptor, Emr1, Gpf480
    基因ID
    13733
    NCBI登录号
    NP_034260
    UniProt
    Q61549
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