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Desmoplakin 抗体 (Internal Region)

DSP 适用: 人, 小鼠, 大鼠 IHC (p), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN1106985
发货至: 中国
  • 抗原 See all Desmoplakin (DSP) 抗体
    Desmoplakin (DSP)
    抗原表位
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1672-1684, Internal Region
    适用
    • 33
    • 16
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 28
    • 4
    • 2
    山羊
    克隆类型
    • 30
    • 4
    多克隆
    标记
    • 23
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Desmoplakin antibody is un-conjugated
    应用范围
    • 15
    • 11
    • 11
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    序列
    C-QESVKQAHLR NEH Remarks: Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (100%), Marmoset (100%), Monkey (92%), Mouse (92%), Rat (92%), Hamster (92%), Elephant (92%), Dog (92%), Horse (92%), Rabbit (92%), Opossum (92%), Platypus (92%), Panda (85%), Bat (85%), Turkey (85%), Chicken (85%).
    特异性
    This antibody is expected to recognize reported isoform I (NP_004406.2) only.
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Rat.
    Species reactivity (tested):Human.
    纯化方法
    Immunoaffinity Chromatography
    免疫原
    Synthetic peptide from the internal region of Human DSP / Desmoplakin (NP_004406.2). Genename: DSP
    Top Product
    Discover our top product DSP Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Desmoplakin (DSP)
    别名
    Desmoplakin (DSP 产品)
    别名
    DP antibody, DPI antibody, DPII antibody, DSP antibody, dpi antibody, dpii antibody, 2300002E22Rik antibody, 5730453H04Rik antibody, AA407887 antibody, AA407888 antibody, AW109828 antibody, im:6911953 antibody, sb:cb570 antibody, wu:fc17a08 antibody, wu:fk73d01 antibody, desmoplakin antibody, Desmoplakin antibody, ORF113 antibody, desmoplakin a antibody, ORF112 DESMOPLAKIN antibody, orf102 antibody, orf91; similar to Cydia pomonella granulovirus orf112 antibody, ORF62 antibody, ORF-66 antibody, ORF57 antibody, agip105 antibody, similar to XcORF133; similar to HaGV desmoplakin antibody, desmoplakin L homeolog antibody, ORF96 antibody, DSP antibody, PhopGV104 antibody, ORF-59 desmoplakin antibody, desmop antibody, Dsp antibody, dsp antibody, desmoplakin antibody, dspa antibody, orf112 desmoplakin antibody, ClgVgp102 antibody, COGV_gp091 antibody, APNV_p087 antibody, CBNV_gp066 antibody, EONV_gp057 antibody, OLNV_gp066 antibody, AgipMNPV_gp105 antibody, HaMNV_gp106 antibody, EupsNPV_gp065 antibody, PsunGV_gp139 antibody, dsp.L antibody, ClanGV_gp096 antibody
    背景
    Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in this gene are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus.Synonyms: 250/210 kDa paraneoplastic pemphigus antigen, DP, DSP
    基因ID
    1832
    NCBI登录号
    NP_001008844
    途径
    Cell-Cell Junction Organization
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