CLCN3 抗体 (AA 98-115)
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- 抗原 See all CLCN3 抗体
- CLCN3 (Chloride Channel 3 (CLCN3))
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抗原表位
- AA 98-115
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CLCN3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (fixed cells) (IF/ICC)
- 原理
- Anti-Chloride Channel Protein 3 Mouse Monoclonal Antibody
- 特异性
- This antibody recognizes human, mouse, and rat Clcn3. It does not cross-react with Clcn4 or Clcn5.
- 交叉反应
- 人, 小鼠, 大鼠
- 交叉反应 （详细）
- No cross Reactivity with Cav3.2
- 纯化方法
- Purified by Protein G affinity chromatography.
- 免疫原
- Synthetic peptide correspond- ing to aa 98-115 (cytoplasmic N-terminus) of rat Clcn3 (accession no. NP_445815.2).
- 克隆位点
- S258-5
- 亚型
- IgG1
- Top Product
- Discover our top product CLCN3 Primary Antibody
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anti-Chloride Channel 3 (CLCN3) (C-Term) antibody
CLCN3 适用: 大鼠, 人, 小鼠, 豚鼠, 兔, 犬, 斑马鱼, 马, Cow, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel 3 (CLCN3) (N-Term) antibodyCLCN3 适用: 大鼠, 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel 3 (CLCN3) (AA 98-115) antibodyCLCN3 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S258-5 unconjugated
anti-Chloride Channel 3 (CLCN3) (AA 98-115) antibody (HRP)CLCN3 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S258-5 HRP
anti-Chloride Channel 3 (CLCN3) (AA 98-115) antibody (FITC)CLCN3 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S258-5 FITC
anti-Chloride Channel 3 (CLCN3) (AA 98-115) antibody (Alkaline Phosphatase (AP))CLCN3 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S258-5 Alkaline Phosphatase (AP)
anti-Chloride Channel 3 (CLCN3) (AA 98-115) antibody (Biotin)CLCN3 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S258-5 Biotin
anti-Chloride Channel 3 (CLCN3) (AA 98-115) antibody (PE)CLCN3 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S258-5 PE
anti-Chloride Channel 3 (CLCN3) (AA 98-115) antibody (APC)CLCN3 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S258-5 APC
anti-Chloride Channel 3 (CLCN3) (AA 98-115) antibody (PerCP)CLCN3 适用: 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S258-5 PerCP
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- 应用备注
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Immunoblotting: use at 1-2 μg/mL. A band of ~90 kDa is detected.
Immunohistochemistry: use at 1-10 μg/mL.
These are recommended concentrations. User should determine optimal concentrations for their application.
Positive control: Rat brain membranes. - 限制
- 仅限研究用
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- 状态
- Liquid
- 溶解方式
- Dilute in PBS or medium which is identical to that used in the assay system.
- 浓度
- Lot specific
- 缓冲液
- PBS, pH 7.4, 50 % glycerol, 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- This antibody is stable for at least one (1) year at -20°C.
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- 抗原
- CLCN3 (Chloride Channel 3 (CLCN3))
- 别名
- Chloride Channel Protein 3 (Clcn3) (CLCN3 产品)
- 别名
- CLC3 antibody, ClC-3 antibody, Clc3 antibody, CLCN3 antibody, fb78c02 antibody, wu:fb78c02 antibody, clc3 antibody, clc-3 antibody, chloride voltage-gated channel 3 antibody, chloride channel, voltage-sensitive 3 antibody, chloride channel 3 antibody, chloride channel protein 3 antibody, chloride channel, voltage-sensitive 3 S homeolog antibody, CLCN3 antibody, Clcn3 antibody, clcn3 antibody, PTRG_03131 antibody, BDBG_05668 antibody, MCYG_04420 antibody, clcn3.S antibody
- 背景
- H(+)/Cl(-) exchange transporter 3,[Isoform 1]: Strongly outwardly rectifying, electrogenic H(+)/Cl(-)exchanger which mediates the exchange of chloride ions against protons (PubMed:10915634). The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons (By similarity). The presence of conserved gating glutamate residues is typical for family members that function as antiporters (By similarity). {UniProtKB:P51790, PubMed:10915634}., [Isoform 2]: Strongly outwardly rectifying, electrogenic H(+)/Cl(-)exchanger which mediates the exchange of chloride ions against protons (PubMed:10915634). May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C (PubMed:8155321). It could help neuronal cells to establish short-term memory (PubMed:8155321). {PubMed:10915634, PubMed:8155321}.,Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. Clcn3 mediates the exchange of chloride ions against protons and functions as an antiporter, contributing to the acidification of the endosome and synaptic vesicle lumen. It may play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C.,[Isoform 1]: Lysosome membrane, Late endosome membrane, Cell membrane, Early endosome membrane,Chloride channel protein 3, ClC-3, Chloride transporter ClC-3
- NCBI登录号
- NP_445815
- UniProt
- P51792
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