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Prosaposin 抗体 (AA 325-524)

PSAP 适用: 人 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 4D5F4 unconjugated
产品编号 ABIN1098150
发货至: 中国
  • 抗原 See all Prosaposin (PSAP) 抗体
    Prosaposin (PSAP)
    抗原表位
    • 15
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 325-524
    适用
    • 41
    • 25
    • 24
    • 1
    • 1
    • 1
    宿主
    • 43
    • 12
    • 1
    小鼠
    克隆类型
    • 46
    • 10
    单克隆
    标记
    • 29
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Prosaposin antibody is un-conjugated
    应用范围
    • 43
    • 22
    • 15
    • 14
    • 14
    • 11
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human PSAP (AA: 325-524 ) expressed in E. coli.
    克隆位点
    4D5F4
    亚型
    IgG1
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:50-1:500, FCM: 1:200 - 1:400
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Xu, Deng, Mao, Zhang, Wang, Wang, Mu, Deng, Ma: "The interaction of the second Kunitz-type domain (KD2) of TFPI-2 with a novel interaction partner, prosaposin, mediates the inhibition of the invasion and migration of human fibrosarcoma cells." in: The Biochemical journal, Vol. 441, Issue 2, pp. 665-74, (2011) (PubMed).

    Hu, Delorme, Liu, Liu, Velasco-Gonzalez, Garai, Pullikuth, Koochekpour: "Prosaposin down-modulation decreases metastatic prostate cancer cell adhesion, migration, and invasion." in: Molecular cancer, Vol. 9, pp. 30, (2010) (PubMed).

  • 抗原
    Prosaposin (PSAP)
    别名
    PSAP (PSAP 产品)
    别名
    GLBA antibody, SAP1 antibody, AI037048 antibody, SGP-1 antibody, SGP1A antibody, cb759 antibody, wu:fa14a06 antibody, wu:fb36e02 antibody, wu:fb58g07 antibody, PSAP antibody, PSP-A antibody, SFTPA1B antibody, SP-A antibody, prosaposin antibody, surfactant protein A1 antibody, PSAP antibody, Psap antibody, psap antibody, LOC100011417 antibody, LOC100304726 antibody, LOC100526719 antibody, SFTPA1 antibody
    背景

    Description: This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. , ,

    Aliases: GLBA, SAP1

    分子量
    58.1 kDa
    基因ID
    5660
    HGNC
    5660
    途径
    Positive Regulation of Endopeptidase Activity
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