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豚鼠 anti-人 IgG (Heavy Chain) Antibody (Biotin)

ELISA, IHC, WB Polyclonal IgG Biotin
产品编号 ABIN1045730
发货至: 中国
  • 抗原 See all IgG products
    IgG
    抗原表位
    • 2333
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    • 411
    • 188
    • 129
    • 122
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    • 6
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Heavy Chain
    适用
    • 692
    • 671
    • 558
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    宿主
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    • 33
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    • 21
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    • 15
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    • 1
    豚鼠
    克隆类型
    • 3346
    • 164
    • 1
    多克隆
    标记
    • 556
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    Biotin
    应用范围
    • 1836
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    • 234
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    ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
    纯化方法
    Caprylic Acid Ammonium Sulfate Precipitation
    免疫原
    Human igg heavy chain
    亚型
    IgG
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    0.03 % Proclin 300, 50 % Glycerol, 0.01 M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid freeze and thaw cycles.
    储存条件
    -20 °C
    储存方法
    Shipped at 4 °C. Upon delivery aliquot and store at -24 °C or -84 °C.
  • 抗原
    IgG
    Abstract
    IgG 产品
    物质类
    Antibody
    背景
    Serum immunoglobulin IgG is the main component, accounting for total serum immunoglobulin content of 75 %. 40 ~ 50 % of the distribution in the serum, and the remaining distributed in the organization. Molecular weight of about 150 kDa. Human serum IgG mainly single, normal, including four subtypes of IgG, IgG1 accounted for its 60 ~ 70 %, IgG2 accounted for 15 ~ 20 %, IgG3 accounted for 5 ~ 10 %, IgG4 accounts for 1 ~ 7 %. These subtypes in the classical pathway of complement activation in the binding capacity varies. IgG mainly by the spleen and lymph nodes in the synthesis of plasma cells, is the only antibodies through the placenta, to prevent birth within weeks of infection play a significant role. Newborn infants after 3 months has been able to synthesize IgG, 2 ~ 3 years old has reached adult levels. Decreased gradually after the age of 40. IgG content of individual differences, the same individual under different conditions, fluctuations are also high. Antigen stimulation in the body produces most of the anti-bacterial, anti-virus, anti-toxin antibodies are IgG. Many autoantibodies, such as systemic lupus erythematosus LE factor, anti-thyroglobulin antibodies are IgG. IgG is the body's main anti-infection immune antibodies.
    分子量
    150 kDa
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