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PYCARD 抗体

(PYD and CARD Domain Containing (PYCARD))
This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm\; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
PYCARD 抗体  (AA 50-195) PYCARD 抗体  (AA 50-195) PYCARD 抗体 (AA 50-195) (ABIN3021617)

PYCARD 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

PYCARD 抗体  (AA 50-195) PYCARD 抗体  (AA 50-195) PYCARD 抗体 (AA 50-195) (ABIN6146515)

PYCARD 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

PYCARD 抗体  (C-Term) PYCARD 抗体  (C-Term) PYCARD 抗体 (C-Term) (ABIN184674)

Verified PYCARD 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

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PYCARD 抗体 by 适用

Find PYCARD 抗体 for a variety of species such as anti-Human PYCARD, anti-Rat PYCARD, anti-Mouse PYCARD. The species listed below are among those available. Click on a link to go to the corresponding products.

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PYCARD 抗体 by 抗原表位

Find PYCARD 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PYCARD 抗体 by 克隆形成能力

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PYCARD 抗体 by 克隆

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Find PYCARD 抗体 with a specific conjugate such as Biotin, FITC, APC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PYCARD 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (1)
  • (7)
Cat. No. ABIN3021617
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (1)
  • (7)
Cat. No. ABIN6146515
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (6)
Cat. No. ABIN184674
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, IP
Validations
  • (7)
Cat. No. ABIN7269756
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (7)
Cat. No. ABIN5542580
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IF
Validations
  • (5)
Cat. No. ABIN1590015
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (4)
Cat. No. ABIN526084
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (1)
  • (3)
Cat. No. ABIN6264533
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7144464
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN526086
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (3)
Cat. No. ABIN7255624
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p), ICC, IHC (fro)
Validations
  • (3)
Cat. No. ABIN2855403
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, IHC (p)
Validations
  • (2)
Cat. No. ABIN7251046
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB
Validations
  • (4)
  • (1)
Cat. No. ABIN6746135
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF
Validations
  • (2)
Cat. No. ABIN7255734
Quantity 200 μL
Datasheet Datasheet

Latest Publications for our PYCARD 抗体

Zhou, Su, Li, Chu, Sun, Zhang, Han, Li, Zou, Niu, Zhang: "PM2.5 exposure impairs sperm quality through testicular damage dependent on NALP3 inflammasome and miR-183/96/182 cluster targeting FOXO1 in mouse." in: Ecotoxicology and environmental safety, Vol. 169, pp. 551-563, (2019) (PubMed).

Wang, Pan, Liu, Zhang, Liu, Lu, Tian, Liu, Jin, An: "AIM2 gene silencing attenuates diabetic cardiomyopathy in type 2 diabetic rat model." in: Life sciences, Vol. 221, pp. 249-258, (2019) (PubMed).

Lage, Dominical, Wong, Sereti: "Evaluation of Canonical Inflammasome Activation in Human Monocytes by Imaging Flow Cytometry." in: Frontiers in immunology, Vol. 10, pp. 1284, (2019) (PubMed).

Cornelius, Baik, Travis, White, Young, Austin Pierce, Shields, Poudel, Williams: "NLRP3 inflammasome activation in platelets in response to sepsis." in: Physiological reports, Vol. 7, Issue 9, pp. e14073, (2019) (PubMed).

Wang, Zhang, Meng, Wang, Li, Liu, Liu: "Ozone protects the rat lung from ischemia-reperfusion injury by attenuating NLRP3-mediated inflammation, enhancing Nrf2 antioxidant activity and inhibiting apoptosis." in: European journal of pharmacology, Vol. 835, pp. 82-93, (2018) (PubMed).

Liang, Liang, Zhang, Deng, He, Chen, Liu, Lin, Yang et al.: "Oral Administration of Compound Probiotics Ameliorates HFD-Induced Gut Microbe Dysbiosis and Chronic Metabolic Inflammation via the G Protein-Coupled Receptor 43 in Non-alcoholic Fatty Liver Disease ..." in: Probiotics and antimicrobial proteins, (2018) (PubMed).

Cohen, Boland, Boland, Takahashi, Tovchigrechko, Lee, Wilde, Mazaitis, Jones-Nelson, Tkaczyk, Raja, Stover, Sellman: "S. aureus Evades Macrophage Killing through NLRP3-Dependent Effects on Mitochondrial Trafficking." in: Cell reports, Vol. 22, Issue 9, pp. 2431-2441, (2018) (PubMed).

Kariya, Okano, Zhao, Maeda, Kataoka, Higaki, Noda, Makihara, Nishizaki: "NLRP3 inflammasome expression in lipopolysaccharide-induced otitis media." in: Acta oto-laryngologica, Vol. 138, Issue 12, pp. 1061-1065, (2018) (PubMed).

MacPherson, Westbom, Kogan, Shukla: "Actin polymerization plays a significant role in asbestos-induced inflammasome activation in mesothelial cells in vitro." in: Histochemistry and cell biology, Vol. 147, Issue 5, pp. 595-604, (2018) (PubMed).

Deng, Zou, Xiong, Wang, Engelhardt, Ye, Yan, Qiu: "Human Parvovirus Infection of Human Airway Epithelia Induces Pyroptotic Cell Death by Inhibiting Apoptosis." in: Journal of virology, Vol. 91, Issue 24, (2017) (PubMed).

Aliases for PYCARD 抗体

PYD and CARD domain containing (PYCARD) 抗体
PYD and CARD domain containing (Pycard) 抗体
PYD and CARD domain containing (pycard) 抗体
9130417A21Rik 抗体
ASC 抗体
Asc 抗体
asc1 抗体
CARD5 抗体
masc 抗体
TMS 抗体
TMS-1 抗体
TMS1 抗体
TNS1 抗体
zAsc 抗体
zgc:109874 抗体
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