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CMA1 抗体

(Chymase 1, Mast Cell (CMA1))
This gene product is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies. This gene maps to 14q11.2 in a cluster of genes encoding other proteases. [provided by RefSeq, Jul 2008].
CMA1 抗体  (Internal Region) CMA1 抗体  (Internal Region) CMA1 抗体 (Internal Region) (ABIN768626)

Verified CMA1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

CMA1 抗体 CMA1 抗体 CMA1 抗体 (ABIN7073506)

CMA1 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

CMA1 抗体  (C-Term) CMA1 抗体  (C-Term) CMA1 抗体 (C-Term) (ABIN6263136)

CMA1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

CMA1 抗体 by Grade

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CMA1 抗体 by 适用

Find CMA1 抗体 for a variety of species such as anti-Human CMA1, anti-Mouse CMA1, anti-Rat CMA1. The species listed below are among those available. Click on a link to go to the corresponding products.

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CMA1 抗体 by 抗原表位

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CMA1 抗体 by 克隆形成能力

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Popular CMA1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (4)
Cat. No. ABIN768626
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse, Rat
Application IHC, IF
Validations
  • (3)
Cat. No. ABIN7073506
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN6263136
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN7266394
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (1)
Cat. No. ABIN7445774
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (1)
Cat. No. ABIN7436312
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7147734
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN7147732
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (1)
Cat. No. ABIN7436315
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6242796
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IHC (p)
Validations
  • (1)
Cat. No. ABIN2619354
Quantity 250 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6138762
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, IHC (p)
Validations
Cat. No. ABIN6942587
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application
Validations
Cat. No. ABIN7177107
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application ELISA
Validations
Cat. No. ABIN7177106
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CMA1 抗体

Germundson, Smith, Vendsel, Kelsch, Combs, Nagamoto-Combs: "Oral sensitization to whey proteins induces age- and sex-dependent behavioral abnormality and neuroinflammatory responses in a mouse model of food allergy: a potential role of mast cells." in: Journal of neuroinflammation, Vol. 15, Issue 1, pp. 120, (2019) (PubMed).

Moretti, Renga, Oikonomou, Galosi, Pariano, Iannitti, Borghi, Puccetti, De Zuani, Pucillo, Paolicelli, Zelante, Renauld, Bereshchenko, Sportoletti, Lucidi, Russo, Colombo, Fiscarelli, Lass-Flörl et al.: "A mast cell-ILC2-Th9 pathway promotes lung inflammation in cystic fibrosis. ..." in: Nature communications, Vol. 8, pp. 14017, (2017) (PubMed).

McLeod, Bhutto, Edwards, Gedam, Baldeosingh, Lutty: "Mast Cell-Derived Tryptase in Geographic Atrophy." in: Investigative ophthalmology & visual science, Vol. 58, Issue 13, pp. 5887-5896, (2017) (PubMed).

Sansoè, Aragno, Mastrocola, Mengozzi, Novo, Parola: "Role of Chymase in the Development of Liver Cirrhosis and Its Complications: Experimental and Human Data." in: PLoS ONE, Vol. 11, Issue 9, pp. e0162644, (2016) (PubMed).

Zhao, Wang, Lin, Groban: "GPR30 decreases cardiac chymase/angiotensin II by inhibiting local mast cell number." in: Biochemical and biophysical research communications, Vol. 459, Issue 1, pp. 131-6, (2015) (PubMed).

Zheng, Wei, Hase, Shi, Killingsworth, Litovsky, Powell, Kobayashi, Ferrario, Rab, Aban, Collawn, DellItalia: "Chymase mediates injury and mitochondrial damage in cardiomyocytes during acute ischemia/reperfusion in the dog." in: PLoS ONE, Vol. 9, Issue 4, pp. e94732, (2014) (PubMed).

Wang, Jessup, Zhao, Da Silva, Lin, MacNamara, Ahmad, Chappell, Ferrario, Groban: "Characterization of the cardiac renin angiotensin system in oophorectomized and estrogen-replete mRen2.Lewis rats." in: PLoS ONE, Vol. 8, Issue 10, pp. e76992, (2013) (PubMed).

Heikkilä, Lätti, Leskinen, Hakala, Kovanen, Lindstedt: "Activated mast cells induce endothelial cell apoptosis by a combined action of chymase and tumor necrosis factor-alpha." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 28, Issue 2, pp. 309-14, (2008) (PubMed).

Hsieh, Sharma, Gibbons, Goggans, Erzurum, Haque: "Human airway epithelial cell determinants of survival and functional phenotype for primary human mast cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 40, pp. 14380-5, (2005) (PubMed).

Aliases for CMA1 抗体

chymase 1 (CMA1) 抗体
chymase 1 (Cma1) 抗体
chymase 1, mast cell (CMA1) 抗体
chymase 1, mast cell (Cma1) 抗体
chymase-like (LOC100008644) 抗体
chymase 抗体
Chymase 抗体
CMA1 抗体
CYH 抗体
Mcp-5 抗体
MCP3P 抗体
Mcp5 抗体
Mcpt5 抗体
MCT1 抗体
MMCP-5 抗体
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