IRDye 800CW BoneTag Optical Probe

ABIN2169596 产品详细信息, 供应商: Log in to see
BioImaging (BI)
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Supplier Product No.
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品牌 BrightSite™,BoneTag™
特异性 Bone
产品特性 Calcium-chelating compounds have been used effectively for the detection of bone mineralization, growth, and morphological changes, including tetracycline derivatives, xylenol orange, alizarin, calcein, and fluorescein. These characteristics have been used to produce a near infrared (NIR) optical bone marker for small animal imaging. Using MC3T3-E1 (osteoblasts) in in vitro cell-based assays, the IRDye BoneTag shows specific binding characteristics. In vivo testing of IRDye BoneTag optical probes are effective for skeletal labeling for imaging, which is unabated several weeks post-administration.
calcium-chelating compound
Optical Probe
Upon receipt, store at -20 °C prior to reconstitution. Reconstituted product should be used immediately.
纯化方法 0.2 μm nylon membrane
应用备注 in vivo: 2 nmol per mouse (25 grams)
限制 仅限研究用
状态 Lyophilized
溶解方式 Reconstitute with 0.5 mL sterile 1X PBS
浓度 0.02 nM/μL
缓冲液 PBS
注意事项 Protect from light.
储存条件 -20 °C
Immunofluorescence (IF) image for IRDye 800CW BoneTag Optical Probe (ABIN2169596) IRDye 800CW BoneTag Optical Probe
有引用在: Kovar, Xu, Draney, Cupp, Simpson, Olive: "Near-infrared-labeled tetracycline derivative is an effective marker of bone deposition in mice." in: Analytical biochemistry, Vol. 416, Issue 2, pp. 167-73, 2011 (PubMed).