anti-s100-a1 (S10A1) 抗体

The protein encoded by S10A1 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. 再加上,我们可以发s100-a1 蛋白 (1)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
S10A1 6271 P23297
S10A1 20193 P56565
S10A1 295214 P35467
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产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 IC, IF, WB Immunofluorescent analysis of S100-A1 staining in HEK293T cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of S100-A1 expression in HEK293T (A), mouse brain (B), rat brain (C), C6 (D) whole cell lysates. 200 μL Log in to see 13至14个工作日
Cow 非结合性 IHC, WB Immunohistochemical analysis of S100-A1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the Western blot analysis of S100-A1 expression in Hela (A) whole cell lysates. 200 μL Log in to see 13至14个工作日
非结合性 IHC, WB   200 μL Log in to see 13至14个工作日


Human s100-a1 (S10A1) interaction partners

  1. Data found that S100A1 was upregulated in hepatocellular carcinoma (HCC) tissues, and its upregulation was associated with large tumor size, low differentiation, and shorter survival rates. Further results supports the hypothesis that S100A1 functions as an oncogene and may be a biomarker for the prognosis of patients with HCC. S100A1 exerted its oncogenic function by interacting with LATS1 and activating Hippo pathway.

  2. The results indicate that changes in the circulating level of S100A1 (显示 S100A1 抗体) protein occur in metabolic syndrome patients. The strong correlation between serum zinc-alpha2-glycoprotein and S100A1 (显示 S100A1 抗体) might suggest that production or release of these two proteins could be related mechanistically.

  3. The results indicated that S100A1 (显示 S100A1 抗体) enhanced the ovarian cancer cell proliferation and migration.

  4. found that S100B (显示 S100B 抗体) plays a crucial role in blocking the interaction site between RAGE (显示 AGER 抗体) V domain and S100A1 (显示 S100A1 抗体). A cell proliferation assay WST (显示 EEF1A2 抗体)-1 also supported our results. This report could potentially be useful for new protein development for cancer treatment

  5. Study provides evidence that mir-363 and its target S100A1 are under the regulatory function of FOXD2-AS1 aggravating nasopharyngeal carcinoma carcinogenesis.

  6. X-ray crystal structure of human calcium-bound S100A1 (显示 S100A1 抗体) has been reported.

  7. a molecular mechanism for the potential regulation of TRPM1 (显示 TRPM1 抗体) by S100A1 (显示 S100A1 抗体)

  8. Data suggest that calcium signaling plays important role in prevention of protein misfolding; complexes of S100A1 (显示 S100A1 抗体) and STIP1 (显示 STIP1 抗体) are key players in this pathway; the stoichiometry of S100A1 (显示 S100A1 抗体)/STIP1 (显示 STIP1 抗体) interaction appears to be three S100A1 (显示 S100A1 抗体) dimers plus one STIP1 (显示 STIP1 抗体) monomer; each S100A1 (显示 S100A1 抗体)-STIP1 (显示 STIP1 抗体)-binding interaction is entropically driven. (S100A1 (显示 S100A1 抗体) = S100 calcium binding protein A1 (显示 S100A1 抗体); STIP1 (显示 STIP1 抗体) = stress-induced-phosphoprotein 1 (显示 STIP1 抗体)) [REVIEW]

  9. Data suggest that three dimers of S100A1 (S100 calcium binding protein A1 (显示 S100A1 抗体)) associate with one molecule of STIP1 (显示 STIP1 抗体) (stress-inducible phosphoprotein 1) in a calcium-dependent manner; individual STIP1 (显示 STIP1 抗体) TPR (tetratricopeptide repeat) domains, TPR1, TPR2A and TPR2B, bind a single S100A1 (显示 S100A1 抗体) dimer with significantly different affinities; TPR2B domain possesses highest affinity for S100A1 (显示 S100A1 抗体).

  10. Results identified amino acids motif in S100A1 (显示 S100A1 抗体) for protein binding to 2-oxohistidine which appears to be an evolutionarily conserved capacity from bacteria to human.

Cow (Bovine) s100-a1 (S10A1) interaction partners

  1. identified S100A1 (显示 S100A1 抗体), but not calmodulin (显示 KRIT1 抗体) or other S100 proteins, as a potent molecular chaperone (显示 HSP90AA1 抗体) and a new member of the Hsp70 (显示 HSP70 抗体)/Hsp90 (显示 HSP90 抗体) multichaperone complex (S100A1 (显示 S100A1 抗体))

  2. Results suggest that S100A1 (显示 S100A1 抗体) can act as a linker between the calcium and redox signalling pathways.

  3. beta-mercaptoethanol modification of apo (显示 C9orf3 抗体)-S100A1 (显示 S100A1 抗体) makes its structure more similar to that of holo-S100A1 (显示 S100A1 抗体), so that it becomes much better adjusted for calcium coordination.

Mouse (Murine) s100-a1 (S10A1) interaction partners

  1. Data (including data from studies using knockout mice) suggest that S100A1 (显示 S100A1 抗体) (S-100 calcium-binding protein (显示 GUCA1B 抗体) A1 (显示 BCL2A1 抗体), alpha chain (显示 FCGRT 抗体)) is involved in protein kinase A- (RIIalpha and RIIbeta (显示 PRKAR2B 抗体))-dependent signaling resulting in nuclear redistribution/influx of HDAC4 (histone deacetylase 4 (显示 HDAC5 抗体)) in skeletal muscle fibers.

  2. S100A1 (显示 S100A1 抗体)-KO exhibited increased right ventricular (RV) weight and elevated RV pressure in the absence of altered left ventricular filling pressures, increase in wall thickness of muscularized pulmonary arteries and a reduction in microvascular perfusion.

  3. S100A1 (显示 S100A1 抗体) and S100B (显示 S100B 抗体) are dispensable for endochondral ossification during skeletal development.

  4. S100A1 ablationalso reduced plaque associated and increased non-plaque associated PO4-Akt and PO4-GSK3beta staining.

  5. Patients with acute myocardial infarction (MI) showed significantly increased S100A1 (显示 S100A1 抗体) serum levels. Experimental MI in mice induced comparable S100A1 (显示 S100A1 抗体) release. S100A1 (显示 S100A1 抗体) signaling in cardiac fibroblasts occurs through endosomal TLR4 (显示 TLR4 抗体)/MyD88 (显示 MYD88 抗体).

  6. hypoxia-induced MiR (显示 MLXIP 抗体)-138 is an essential mediator of EC dysfunction via its ability to target the 3'UTR (显示 UTS2R 抗体) of S100A1 (显示 S100A1 抗体).

  7. Report downregulation of S100A1 expression in critical limb ischemia impairs postischemic angiogenesis via compromised proangiogenic endothelial cell function and nitric oxide synthase regulation.

  8. S100A1 (显示 S100A1 抗体) and calmodulin bind to an overlapping domain on the ryanodine receptor (显示 RYR3 抗体) type 1 to tune the Ca2 (显示 CA2 抗体)+ release process, and thereby regulate skeletal muscle function. (Review)

  9. The RyR1 (显示 RYR1 抗体)-L3625D mutation removed both an early activating effect of S100A1 (显示 S100A1 抗体) and calmodulin and delayed the suppression of RyR1 (显示 RYR1 抗体) Ca2 (显示 CA2 抗体)+ release, providing new insights into calmodulin and S100A1 (显示 S100A1 抗体) regulation of skeletal muscle excitation-contraction coupling.

  10. Data suggest that the absence of S100A1 (显示 S100A1 抗体) suppresses physiological AP-induced Ca(2 (显示 CA2 抗体)+) release flux, resulting in impaired contractile activation and force production in skeletal muscle.

s100-a1 (S10A1) 抗原简介


The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.

Gene names and symbols associated with anti-s100-a1 (S10A1) 抗体

  • S100 calcium binding protein A1 (S100A1) 抗体
  • S100 calcium binding protein A1 (S100a1) 抗体
  • AI266795 抗体
  • S100 抗体
  • S100-alpha 抗体
  • S100a 抗体

Protein level used designations for anti-s100-a1 (S10A1) 抗体

S-100 protein alpha chain , S-100 protein subunit alpha , S100 alpha , S100 calcium-binding protein A1 , S100 protein, alpha polypeptide , protein S100-A1

100858258 Gallus gallus
6271 Homo sapiens
480141 Canis lupus familiaris
528735 Bos taurus
20193 Mus musculus
295214 Rattus norvegicus
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