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ARHGAP1 encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. 再加上，我们可以发ARHGAP1 蛋白 (4) 和 和数多这个蛋白质的别的产品。
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Human Polyclonal ARHGAP1 Primary Antibody for ELISA, WB - ABIN559937
Kang, Bae, Yi, Yang, Oh, Takaesu, Zhou, Low, Krauss: A Cdo-Bnip-2-Cdc42 signaling pathway regulates p38alpha/beta MAPK activity and myogenic differentiation. in The Journal of cell biology 2008
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Human Polyclonal ARHGAP1 Primary Antibody for ICC, IF - ABIN4281487
Härmä, Knuuttila, Virtanen, Mirtti, Kohonen, Kovanen, Happonen, Kaewphan, Ahonen, Kallioniemi, Grafström, Lötjönen, Nees: Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models. in Oncogene 2012
identified ARHGAP1, which is a negative regulator of CDC42 (显示 CDC42 抗体), as a novel, direct target of miR (显示 MLXIP 抗体)-130b
to complete invasion of the endothelium, staphylococci reorient recycling endocytic vesicles to recruit Cdc42GAP.
we identified novel associations in WLS (显示 WLS 抗体) , ARHGAP1 , and 5' of MEF2C (显示 MEF2C 抗体) ( P- values < 8x10 - 5 ; false discovery rate (FDR) q-values < 0.01) that were much more strongly associated with BMD (显示 BEST1 抗体) compared to the GWAS SNPs.
study shows that HMHA1 (显示 HMHA1 抗体) acts as a RhoGAP to regulate GTPase (显示 RACGAP1 抗体) activity, cytoskeletal remodeling and cell spreading, which are crucial functions in normal hematopoietic and cancer cells
The interaction of RhoGap protein (显示 ARHGAP26 抗体) stabilizes the tetrameric conformation of p53 (显示 TP53 抗体) and enhances its DNA-binding activity, thereby inducing cell-cycle arrest and apoptosis.
In PC3 (显示 PCSK1 抗体) cells, ARHGAP21 (显示 ARHGAP21 抗体) presented GAP activity for RhoA (显示 RHOA 抗体) and RhoC (显示 RHOC 抗体) and induced changes in cell morphology. Moreover, its silencing altered the expression of genes involved in cell proliferation and cytoskeleton organization
RhoGAP Stard13 (显示 STARD13 抗体) temporally and spatially regulates Rho activity in the developing pancreas to ensure that morphogenesis and establishment of tissue architecture are coordinated with organ growth.
Rho proteins and ROK (显示 GRK1 抗体) play a pivotal role in this signaling cascade
PA and Rap1 (显示 RABGEF1 抗体) cooperatively regulate RA-RhoGAP activity for promoting neurite outgrowth.
Mutation of three residues of CDC42GAP involved in specific interactions of CDC42GAP with switch domain residues of Cdc42 (显示 CDC42 抗体), as well as individual mutations of each of these residues, yields GAPs that are defective in stimulating GTP (显示 AK3 抗体) hydrolysis.
These results demonstrate a different requirement of Cdc42 (显示 CDC42 抗体) activity in primary mouse embryo fibroblasts suggesting that Cdc42 (显示 CDC42 抗体) plays cell-type-specific signaling roles.
Rho is activated in a discrete apical region of premigratory neural crest cells. Arhgap1 restricts Rho activation to apical areas, and this restriction is necessary for detachment.
This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein contains a SRC homology 3 domain and interacts with Bcl-2-associated protein family members.
CDC42 GTPase-activating protein
, GTPase-activating protein rhoGAP
, GTPase-activating protein rhoOGAP
, GTPase-activating protein, Rho, 1
, rho GTPase-activating protein 1
, rho-related small GTPase protein activator
, rho-type GTPase-activating protein 1
, Cdc42 GTPase-activating protein
, Rho GTPase activating protein 1 S homeolog