anti-gamma-Glutamylcyclotransferase (GGCT) 抗体

The protein encoded by GGCT catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. 再加上,我们可以发gamma-Glutamylcyclotransferase 蛋白 (13)gamma-Glutamylcyclotransferase 试剂盒 (8)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
GGCT 110175 Q9D7X8
GGCT 362368  
GGCT 79017 O75223
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Showing 10 out of 67 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 EIA, WB Western blot analysis of GGCT Antibody (C-term) in 293 cell line lysates (35ug/lane). GGCT (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6至8个工作日
$390.50
详细
非结合性 WB Western blot analysis of GGCT Antibody (C-term) (ABIN653628) in 293 cell line lysates (35 µg/lane). GGCT (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10至11个工作日
$335.50
详细
非结合性 ELISA, IHC (p), IP, WB Immunochemical staining of human GGCT in human lung cancer with rabbit polyclonal antibody (0.1 µg/mL, formalin-fixed paraffin embedded sections). Immunochemical staining of human GGCT in human hepatoma with rabbit polyclonal antibody (0.1 µg/mL, formalin-fixed paraffin embedded sections). 100 μg Log in to see 20至21个工作日
$218.90
详细
非结合性 IHC, IHC (p), WB Western Blot: gamma-Glutamylcyclotransferase/CRF21/GGCT Antibody [NBP1-86727] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4 Immunohistochemistry-Paraffin: gamma-Glutamylcyclotransferase/CRF21/GGCT Antibody [NBP1-86727] - Staining of human corpus, uterine shows moderate cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 10至13个工作日
$491.63
详细
非结合性 IHC, WB 100 μL Log in to see 16 Days
$407.72
详细
非结合性 IHC, IHC (p), WB Anti-GGCT antibody IHC staining of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100. 200 μL Log in to see 11至14个工作日
$484.00
详细
非结合性 WB Western blot analysis of extracts of various cell lines, using GGCT antibody (ABIN5972861) at 1/1000 dilution. 100 μL Log in to see 11至16个工作日
$412.19
详细
非结合性 WB   50 μg Log in to see 7至9个工作日
$551.83
详细
非结合性 ELISA   100 μg Log in to see 20至21个工作日
$163.90
详细

引用最多的anti-gamma-Glutamylcyclotransferase 抗体

  1. Human Polyclonal GGCT Primary Antibody for IHC, IHC (p) - ABIN4313404 : Gromov, Gromova, Friis, Timmermans-Wielenga, Rank, Simon, Sauter, Moreira: Proteomic profiling of mammary carcinomas identifies C7orf24, a gamma-glutamyl cyclotransferase, as a potential cancer biomarker. in Journal of proteome research 2010 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal GGCT Primary Antibody for IHC, IHC (p) - ABIN4313405 : Amano, Eishi, Yamada, Uchida, Minegishi, Tamura, Kobayashi, Hiroshi, Suzuki, Board: Widespread expression of γ-glutamyl cyclotransferase suggests it is not a general tumor marker. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2011 (PubMed)

更多抗gamma-Glutamylcyclotransferase的相互作用对抗体

Human gamma-Glutamylcyclotransferase (GGCT) interaction partners

  1. GGCT is highly upregulated in HGSC tissues and associated with FIGO stage, lymph node metastasis and ascitic fluid volume. High expression of GGCT is associated with poor survival in HGSC patients.

  2. Taken together, the results indicate that PHB2 (显示 PHB2 抗体) plays a central role in p21 (显示 CDKN1A 抗体) upregulation following GGCT knockdown and as such may promote deregulated proliferation of cancer cells by suppressing p21 (显示 CDKN1A 抗体).

  3. GGCT plays a critical role in glioma cell proliferation and may be a potential cancer therapeutic target.

  4. GGCT is promising as a diagnostic marker and a therapeutic target for various cancers. This review summarizes these interesting findings.

  5. G6PD (显示 G6PD 抗体), GGCT, IDH1 (显示 IDH1 抗体), isocitrate dehydrogenase 2 (显示 IDH2 抗体) (NADP+,mitochondrial) (IDH2 (显示 IDH2 抗体)) and glutathione S-transferase pi 1(GSTP1 (显示 GSTP1 抗体)), five of the critical components of GSH pathway, contribute to chemoresistance.

  6. GGCT plays a critical role in lung cancer cell proliferation.

  7. Transcriptional silencing of the C7orf24 gene in the non-malignant cells is elicited through heterochromatin formation in its promoter region.

  8. increased expression of GGCT was a common event among invasive esophageal squamous cell carcinoma tissues regardless of the depth of invasion. Lymph node metastasis and tumor differentiation correlated with GGCT expression

  9. C7orf24 has been recognized as a potent marker for bladder and breast cancers. Studies on the role of gamma-glutamylcyclotransferace may aid in the control of malignant transformation of these cancers.

  10. GGCT may be a biomarker of tumors in a limited range of organs.

gamma-Glutamylcyclotransferase (GGCT) 抗原简介

蛋白简介

The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with GGCT

  • gamma-glutamylcyclotransferase b (ggctb) 抗体
  • gamma-glutamylcyclotransferase (GGCT) 抗体
  • gamma-glutamylcyclotransferase (ggct) 抗体
  • gamma-glutamyl cyclotransferase (ggct) 抗体
  • gamma-glutamyl cyclotransferase (Ggct) 抗体
  • A030007L17Rik 抗体
  • AA673177 抗体
  • C7orf24 抗体
  • CRF21 抗体
  • fj35c05 抗体
  • GCTG 抗体
  • GGC 抗体
  • ggct 抗体
  • Ggctl1 抗体
  • RGD1304876 抗体
  • RGD1562590 抗体
  • wu:fj35b07 抗体
  • wu:fj35c05 抗体
  • zgc:56140 抗体

Protein level used designations for GGCT

gamma-glutamylcyclotransferase , gamma-glutamyl cyclotransferase , gamma-glutamyl cyclotransferase-like 1 , cytochrome c-releasing factor 21 , gamma -glutamyl cyclotransferase

GENE ID SPECIES
406278 Danio rerio
463327 Pan troglodytes
611603 Canis lupus familiaris
613056 Xenopus (Silurana) tropicalis
695547 Macaca mulatta
100528263 Ictalurus punctatus
110175 Mus musculus
362368 Rattus norvegicus
79017 Homo sapiens
533374 Bos taurus
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