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BACE2 抗体

(beta-Site APP-Cleaving Enzyme 2 (BACE2))
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
BACE2 抗体  (AA 230-396) BACE2 抗体  (AA 230-396) BACE2 抗体 (AA 230-396) (ABIN7434101)

BACE2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

BACE2 抗体  (AA 242-502) BACE2 抗体  (AA 242-502) BACE2 抗体 (AA 242-502) (ABIN7438730)

BACE2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

BACE2 抗体  (AA 240-470) BACE2 抗体  (AA 240-470) BACE2 抗体 (AA 240-470) (ABIN7265880)

BACE2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

BACE2 抗体 by 适用

Find BACE2 抗体 for a variety of species such as anti-Human BACE2, anti-Rat BACE2, anti-Mouse BACE2. The species listed below are among those available. Click on a link to go to the corresponding products.

BACE2 抗体 by 应用范围

Find BACE2 抗体 validated for a specific application such as WB, ELISA, IHC, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

BACE2 抗体 by 抗体来源

Find BACE2 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

BACE2 抗体 by 抗原表位

Find BACE2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

BACE2 抗体 by 克隆形成能力

Find available monoclonal or polyclonal BACE2 抗体. Click on a link to go to the corresponding products.

BACE2 抗体 by 克隆

Find BACE2 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

BACE2 抗体 by 标记

Find BACE2 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular BACE2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7434101
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7438730
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (5)
Cat. No. ABIN7265880
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (4)
Cat. No. ABIN7438664
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7145535
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN462433
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN7072331
Quantity 200 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (3)
  • (1)
Cat. No. ABIN550291
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
  • (1)
Cat. No. ABIN550290
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (3)
Cat. No. ABIN3030160
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Rat
Application ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (1)
Cat. No. ABIN2170478
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN565178
Quantity 50 μL
Datasheet Datasheet
Reactivity Guinea Pig, Human, Monkey, Mouse, Pig, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6743441
Quantity 100 μL
Datasheet Datasheet
Reactivity Bat, Chicken, Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rat
Application WB
Validations
  • (1)
Cat. No. ABIN6743440
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS
Validations
  • (2)
Cat. No. ABIN390067
Quantity 400 μL
Datasheet Datasheet

Latest Publications for our BACE2 抗体

Barbiero, Benussi, Ghidoni, Alberici, Russo, Schettini, Pagano, Parati, Mazzoli, Nicosia, Signorini, Feudatari, Binetti: "BACE-2 is overexpressed in Down's syndrome." in: Experimental neurology, Vol. 182, Issue 2, pp. 335-45, (2003) (PubMed).

Basi, Frigon, Barbour, Doan, Gordon, McConlogue, Sinha, Zeller: "Antagonistic effects of beta-site amyloid precursor protein-cleaving enzymes 1 and 2 on beta-amyloid peptide production in cells." in: The Journal of biological chemistry, Vol. 278, Issue 34, pp. 31512-20, (2003) (PubMed).

Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, (2003) (PubMed).

Acquati, Accarino, Nucci, Fumagalli, Jovine, Ottolenghi, Taramelli: "The gene encoding DRAP (BACE2), a glycosylated transmembrane protein of the aspartic protease family, maps to the down critical region." in: FEBS letters, Vol. 468, Issue 1, pp. 59-64, (2000) (PubMed).

Bennett, Babu-Khan, Loeloff, Louis, Curran, Citron, Vassar: "Expression analysis of BACE2 in brain and peripheral tissues." in: The Journal of biological chemistry, Vol. 275, Issue 27, pp. 20647-51, (2000) (PubMed).

Farzan, Schnitzler, Vasilieva, Leung, Choe: "BACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 17, pp. 9712-7, (2000) (PubMed).

Aliases for BACE2 抗体

beta-site APP-cleaving enzyme 2 (BACE2) 抗体
beta-site APP-cleaving enzyme 2 (Bace2) 抗体
1110059C24Rik 抗体
AEPLC 抗体
AI850424 抗体
ALP56 抗体
ARP1 抗体
ASP1 抗体
ASP21 抗体
BAE2 抗体
CDA13 抗体
CEAP1 抗体
DRAP 抗体
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