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BACE1 抗体

(Beta-secretase 1 (BACE1))
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011].
BACE1 抗体  (AA 22-501) BACE1 抗体  (AA 22-501) BACE1 抗体 (AA 22-501) (ABIN2566113)

BACE1 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 2C1 unconjugated

BACE1 抗体  (AA 112-324) BACE1 抗体  (AA 112-324) BACE1 抗体 (AA 112-324) (ABIN5649334)

BACE1 适用: 人 WB, ELISA, IF, FACS 宿主: 小鼠 Monoclonal 3C1C3 unconjugated

BACE1 抗体  (AA 112-324) BACE1 抗体  (AA 112-324) BACE1 抗体 (AA 112-324) (ABIN2682977)

BACE1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3C1C3 unconjugated

BACE1 抗体 by 适用

Find BACE1 抗体 for a variety of species such as anti-Human BACE1, anti-Mouse BACE1, anti-Rat BACE1. The species listed below are among those available. Click on a link to go to the corresponding products.

BACE1 抗体 by 应用范围

Find BACE1 抗体 validated for a specific application such as WB, ELISA, IHC, FACS. Some of the available applications are listed below. Click on a link to go to the corresponding products.

BACE1 抗体 by 抗体来源

Find BACE1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

BACE1 抗体 by 抗原表位

Find BACE1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

BACE1 抗体 by 克隆形成能力

Find available monoclonal or polyclonal BACE1 抗体. Click on a link to go to the corresponding products.

BACE1 抗体 by 克隆

Find BACE1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

BACE1 抗体 by 标记

Find BACE1 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular BACE1 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), PLA
Validations
  • (6)
Cat. No. ABIN2566113
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF, FACS
Validations
  • (6)
Cat. No. ABIN5649334
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, ICC, FACS
Validations
  • (6)
Cat. No. ABIN2682977
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB, IHC, IF
Validations
  • (6)
Cat. No. ABIN2782766
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), ICC, FACS, IF (cc), IF (p), IHC (fro)
Validations
  • (5)
  • (3)
Cat. No. ABIN725705
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN6137413
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7145531
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Monkey
Application IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN213581
Quantity 50 μg
Datasheet Datasheet
Reactivity Bat, Cow, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN6745737
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (4)
  • (3)
Cat. No. ABIN392201
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (2)
Cat. No. ABIN7432457
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (2)
Cat. No. ABIN6260181
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, PLA
Validations
  • (2)
Cat. No. ABIN525314
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Monkey, Rat
Application IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN213580
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN7265879
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our BACE1 抗体

Ku, Li, Gao, Zhang, Yan, Ji, Li, Sang: "NF-κB-regulated microRNA-574-5p underlies synaptic and cognitive impairment in response to atmospheric PM2.5 aspiration." in: Particle and fibre toxicology, Vol. 14, Issue 1, pp. 34, (2018) (PubMed).

Lu, Cui, Li, Wang, Zhou, Yang, Chen, Zhao, Pei: "An Anti-Parkinson's Disease Drug via Targeting Adenosine A2A Receptor Enhances Amyloid-β Generation and γ-Secretase Activity." in: PLoS ONE, Vol. 11, Issue 11, pp. e0166415, (2017) (PubMed).

Lu, Li, Wang, Pei: "Dopamine D2 receptor and β-arrestin 2 mediate Amyloid-β elevation induced by anti-parkinson's disease drugs, levodopa and piribedil, in neuronal cells." in: PLoS ONE, Vol. 12, Issue 3, pp. e0173240, (2017) (PubMed).

Hong, Shen, Yin, Sun, Ma, Liu: "Effects of RAGE-Specific Inhibitor FPS-ZM1 on Amyloid-β Metabolism and AGEs-Induced Inflammation and Oxidative Stress in Rat Hippocampus." in: Neurochemical research, Vol. 41, Issue 5, pp. 1192-9, (2016) (PubMed).

Yan, Yun, Ku, Li, Sang: "NO2 inhalation promotes Alzheimer's disease-like progression: cyclooxygenase-2-derived prostaglandin E2 modulation and monoacylglycerol lipase inhibition-targeted medication." in: Scientific reports, Vol. 6, pp. 22429, (2016) (PubMed).

Jiao, Kong, Yao, Li, Tao, Yan, Yang: "Osthole decreases beta amyloid levels through up-regulation of miR-107 in Alzheimer's disease." in: Neuropharmacology, Vol. 108, pp. 332-44, (2016) (PubMed).

Schnöder, Hao, Qin, Liu, Tomic, Liu, Fassbender, Liu: "Deficiency of Neuronal p38α MAPK Attenuates Amyloid Pathology in Alzheimer Disease Mouse and Cell Models through Facilitating Lysosomal Degradation of BACE1." in: The Journal of biological chemistry, Vol. 291, Issue 5, pp. 2067-79, (2016) (PubMed).

Li, Cui, Yu, Li, Hou, Wang, Qin, Zhao, Yao, Zhao, Pei: "Traditional Chinese Nootropic Medicine Radix Polygalae and Its Active Constituent Onjisaponin B Reduce β-Amyloid Production and Improve Cognitive Impairments." in: PLoS ONE, Vol. 11, Issue 3, pp. e0151147, (2016) (PubMed).

Tian, Guo, Wu, Ma, Zhao: "Minocycline Alleviates Sevoflurane-Induced Cognitive Impairment in Aged Rats." in: Cellular and molecular neurobiology, (2015) (PubMed).

Prior, Dargusch, Ehren, Chiruta, Schubert: "The neurotrophic compound J147 reverses cognitive impairment in aged Alzheimer's disease mice." in: Alzheimer's research & therapy, Vol. 5, Issue 3, pp. 25, (2014) (PubMed).

Aliases for BACE1 抗体

beta-secretase 1 (BACE1) 抗体
beta-site APP cleaving enzyme 1 (Bace1) 抗体
beta-secretase 1 (Bace1) 抗体
beta-site APP-cleaving enzyme 1 (bace1) 抗体
ASP2 抗体
BACE 抗体
Bace 抗体
BACE1 抗体
C76936 抗体
HSPC104 抗体
MGC145931 抗体
zgc:77409 抗体
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