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ZYX 抗体

(Zyxin (ZYX))
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008].
ZYX 抗体  (AA 1-572) ZYX 抗体  (AA 1-572) ZYX 抗体 (AA 1-572) (ABIN563471)

ZYX 适用: 人 WB, ELISA, IF, IP, RNAi 宿主: 小鼠 Monoclonal 2C10-4A7 unconjugated

ZYX 抗体  (AA 1-572) ZYX 抗体  (AA 1-572) ZYX 抗体 (AA 1-572) (ABIN521634)

ZYX 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2D1 unconjugated

ZYX 抗体  (Internal Region) ZYX 抗体  (Internal Region) ZYX 抗体 (Internal Region) (ABIN6266149)

ZYX 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

ZYX 抗体 by Grade

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ZYX 抗体 by 适用

Find ZYX 抗体 for a variety of species such as anti-Human ZYX, anti-Mouse ZYX, anti-Rat ZYX. The species listed below are among those available. Click on a link to go to the corresponding products.

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ZYX 抗体 by 抗原表位

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ZYX 抗体 by 克隆形成能力

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ZYX 抗体 by 克隆

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ZYX 抗体 by 标记

Find ZYX 抗体 with a specific conjugate such as Biotin, Alexa Fluor 488, Alexa Fluor 555. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular ZYX 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IF, IP, RNAi
Validations
  • (2)
  • (6)
Cat. No. ABIN563471
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (1)
  • (4)
Cat. No. ABIN521634
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (5)
Cat. No. ABIN6266149
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN7260207
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (4)
Cat. No. ABIN3023009
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Rabbit, Rat
Application WB, IHC
Validations
  • (5)
Cat. No. ABIN2775767
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN521633
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN574391
Quantity 50 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application WB
Validations
  • (1)
  • (3)
Cat. No. ABIN2775766
Quantity 100 μL
Datasheet Datasheet
Reactivity Hamster, Human, Mouse, Rat
Application WB, IP, ICC
Validations
  • (11)
  • (2)
Cat. No. ABIN1742558
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN521631
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application IF, IHC (p)
Validations
  • (2)
Cat. No. ABIN5650325
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN1682627
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (3)
Cat. No. ABIN1860974
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC (p), IHC (fro), IF (cc), IF (p)
Validations
  • (1)
Cat. No. ABIN701710
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our ZYX 抗体

Missirlis, Haraszti, Scheele, Wiegand, Diaz, Neubauer, Rechenmacher, Kessler, Spatz: "Substrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectin." in: Scientific reports, Vol. 6, pp. 23258, (2016) (PubMed).

Kenific, Stehbens, Goldsmith, Leidal, Faure, Ye, Wittmann, Debnath: "NBR1 enables autophagy-dependent focal adhesion turnover." in: The Journal of cell biology, Vol. 212, Issue 5, pp. 577-90, (2016) (PubMed).

Fukumoto, Kurisu, Yamada, Takenawa: "α-Actinin-4 enhances colorectal cancer cell invasion by suppressing focal adhesion maturation." in: PLoS ONE, Vol. 10, Issue 4, pp. e0120616, (2015) (PubMed).

Gadhari, Charnley, Marelli, Brugger, Chiquet: "Cell shape-dependent early responses of fibroblasts to cyclic strain." in: Biochimica et biophysica acta, Vol. 1833, Issue 12, pp. 3415-25, (2013) (PubMed).

Mise, Savai, Yu, Schwarz, Kaminski, Eickelberg: "Zyxin is a transforming growth factor-? (TGF-?)/Smad3 target gene that regulates lung cancer cell motility via integrin ?5?1." in: The Journal of biological chemistry, Vol. 287, Issue 37, pp. 31393-405, (2012) (PubMed).

Delaroche, Cantrelle, Subra, Van Heijenoort, Guittet, Jiao, Blanchoin, Chassaing, Lavielle, Auclair, Sagan: "Cell-penetrating peptides with intracellular actin-remodeling activity in malignant fibroblasts." in: The Journal of biological chemistry, Vol. 285, Issue 10, pp. 7712-21, (2010) (PubMed).

Low, Mukhina, Srinivas, Ng, Murata-Hori: "Domain analysis of alpha-actinin reveals new aspects of its association with F-actin during cytokinesis." in: Experimental cell research, Vol. 316, Issue 12, pp. 1925-34, (2010) (PubMed).

Mori, Nakagami, Koibuchi, Miura, Takami, Koriyama, Hayashi, Sabe, Mochizuki, Morishita, Kaneda: "Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis." in: Molecular biology of the cell, Vol. 20, Issue 13, pp. 3115-24, (2009) (PubMed).

Vollenbröker, George, Wolfgart, Saleem, Pavenstädt, Weide: "mTOR regulates expression of slit diaphragm proteins and cytoskeleton structure in podocytes." in: American journal of physiology. Renal physiology, Vol. 296, Issue 2, pp. F418-26, (2009) (PubMed).

Vervenne, Crombez, Delvaux, Janssens, Van de Ven, Petit: "Targeted disruption of the mouse Lipoma Preferred Partner gene." in: Biochemical and biophysical research communications, Vol. 379, Issue 2, pp. 368-73, (2009) (PubMed).

Aliases for ZYX 抗体

Zyxin (zyx-1) 抗体
Zyxin (Zyx) 抗体
zyxin (zyx) 抗体
zyxin (ZYX) 抗体
zyxin (EDI_201420) 抗体
zyxin (Zyx) 抗体
zyxin S homeolog (zyx.S) 抗体
9530098H06Rik 抗体
BcDNA:LD06023 抗体
CG32018 抗体
DLim-1 抗体
Dmel\\CG32018 抗体
DmLIM-1 抗体
ESP-2 抗体
HED-2 抗体
lim 抗体
Lim102EF 抗体
MGC145270 抗体
R75157 抗体
zgc:171680 抗体
ZYX 抗体
zyx 抗体
ZYX102 抗体
Zyx102 抗体
zyx102 抗体
Zyx102EF 抗体
zyxin 抗体
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