WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 1 (WFIKKN1) ELISA试剂盒

WFIKKN1 encodes a secreted multidomain protein consisting of a signal peptide, a WAP domain, a follistatin domain, an immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. 再加上,我们可以发WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 1 抗体 (7)WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 1 蛋白 (2)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
WFIKKN1 117166 Q96NZ8
WFIKKN1 363555 P0C5J5
WFIKKN1 215001 Q8R0S6
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适于 WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 1 相互作用对的更多 ELISA 试剂盒

Human WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 1 (WFIKKN1) interaction partners

  1. In this review, we summarize current knowledge about the WFIKKN proteins and propose that they are "companion" proteins for various growth factors by providing localized and sustained presentation of TGFB (显示 TGFB1 ELISA试剂盒) proteins to their respective receptors, thus regulating the balance between the activation of Smad (显示 SMAD1 ELISA试剂盒) and non-Smad (显示 SMAD1 ELISA试剂盒) pathways by TGFB (显示 TGFB1 ELISA试剂盒).

  2. Data show that the KKN1 fragment generated by BMP1 (显示 BMP1 ELISA试剂盒)-cleavage of WFIKKN1 protein contributes most significantly to the observed enhancer activity.

  3. Data suggest that myostatin (显示 MSTN ELISA试剂盒) binding to its receptor (activin receptors type II) can be blocked by WFIKKN1 but not WFIKKN2 (显示 WFIKKN2 ELISA试剂盒); various forms of myostatin (显示 MSTN ELISA试剂盒) (promyostatin, myostatin (显示 MSTN ELISA试剂盒) pro-domain, and latent/processed myostatin (显示 MSTN ELISA试剂盒)) bind WFIKKN1 but not WFIKKN2 (显示 WFIKKN2 ELISA试剂盒).

  4. data indicate that WFIKKN proteins are antagonists of GDF8 (显示 MSTN ELISA试剂盒) and GDF11 (显示 GDF11 ELISA试剂盒), but in the case of TGFbeta1 (显示 TGFB1 ELISA试剂盒), BMP2 (显示 BMP2 ELISA试剂盒) and BMP4 (显示 BMP4 ELISA试剂盒) they function as growth factor binding proteins

  5. Newly discovered WFIKKNPR gene structure and tissue distribution of gene expression is commpared with that of the WFIKKN gene in adult and fetal tissues and organs.

  6. Data suggest that the physiological target of WFIKKN protein may be trypsin.

  7. three-dimensional structure of a Kunitz domain with a tryptophan residue at the P02 (显示 TPT1 ELISA试剂盒) site of the protease-recognition loop

  8. Both WFIKKN1 and WFIKKN2 (显示 WFIKKN2 ELISA试剂盒) have high affinity for growth and differentiation factors 8 and 11.

Mouse (Murine) WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 1 (WFIKKN1) interaction partners

  1. GASP-1 (显示 GPRASP1 ELISA试剂盒) and GASP-2 are important modulators of GDF-11 (显示 GDF11 ELISA试剂盒) and MSTN (显示 MSTN ELISA试剂盒) activity in vivo.

WAP, Follistatin/kazal, Immunoglobulin, Kunitz and Netrin Domain Containing 1 (WFIKKN1) 抗原简介

Antigen Summary

This gene encodes a secreted multidomain protein consisting of a signal peptide, a WAP domain, a follistatin domain, an immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. These domains have been implicated frequently in inhibition of various types of proteases, suggesting that the encoded protein may be a multivalent protease inhibitor and may control the action of multiple types of serine proteases as well as metalloproteinases.

Gene names and symbols associated with WFIKKN1

  • WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 (WFIKKN1) 抗体
  • WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 (Wfikkn1) 抗体
  • WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 (wfikkn1) 抗体
  • WAP, FS, Ig, KU, and NTR-containing protein 1 (Wfikkn1) 抗体
  • C16orf12 抗体
  • Gasp2 抗体
  • Oc29 抗体
  • RGD1565835 抗体
  • RJD2 抗体
  • WFDC20A 抗体
  • wfikkn 抗体
  • WFIKKN1 抗体
  • zgc:85816 抗体

Protein level used designations for WFIKKN1

GASP-2 , WAP four-disulfide core domain 20A , WAP, FS, Ig, KU, and NTR-containing protein , WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 , WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing protein , growth and differentiation factor-associated serum protein 2 , hGASP-2 , WAP, FS, Ig, KU, and NTR-containing protein 1 , WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 , WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 1 , WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 1-like , mGASP-2 , WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein

GENE ID SPECIES
117166 Homo sapiens
363555 Rattus norvegicus
429301 Gallus gallus
490094 Canis lupus familiaris
540233 Bos taurus
722338 Macaca mulatta
100066872 Equus caballus
100137288 Papio anubis
100473789 Ailuropoda melanoleuca
100490754 Xenopus (Silurana) tropicalis
100619314 Monodelphis domestica
215001 Mus musculus
406570 Danio rerio
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