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VAX1 encodes a homeo-domain containing protein from a class of homeobox transcription factors which are conserved in vertebrates. 再加上，我们可以发VAX1 蛋白 (8)和数多这个蛋白质的别的产品。
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Cow (Bovine) Polyclonal VAX1 Primary Antibody for WB - ABIN2775832
Holland, Booth, Bruford: Classification and nomenclature of all human homeobox genes. in BMC biology 2008
rs4752028 weakly associated with nonsyndromic cleft lip with or without cleft palate in northern Chinese Han population
Our study replicated previous GWAS findings for markers in VAX1 in the Asian population, and identified rare variants in PAX7 and VAX1 that may contribute to the etiology of CL(P).
VAX1 rs10787760, rs6585429 and rs1871345 polymorphisms may be involved in nonsyndromic cleft lip with or without cleft palate in Brazilian patients, but there is no association with polymorphisms in FGF12, VCL, or CX43
The data do not support the hypothesis that highly penetrant rare variants in VAX1 are a cause of nonsyndromic cleft lip with or without cleft palate.
This is the first description of a patient with a VAX1 mutation and establishes VAX1 as a new causative gene for anophthalmia/microphthalmia (A/M) in humans.
vax1 and vax2 are expressed in overlapping domains encompassing the ventral retina, optic stalks and preoptic area; Hh signals act downstream of the Nodal pathway to promote Vax gene expression.
This gene encodes a homeo-domain containing protein from a class of homeobox transcription factors which are conserved in vertebrates. Genes of this family are involved in the regulation of body development and morphogenesis. The most conserved genes, called HOX genes are found in special gene clusters. This gene belongs to the VAX subfamily and lies in the vicinity of the EMX homeobox gene family. Another member of VAX family is located on chromosome 2. The encoded protein may play an important role in the development of anterior ventral forebrain and visual system. Multiple transcript variants encoding different isoforms have been found for this gene.
ventral anterior homeobox containing gene 1
, homeobox protein
, ventral anterior homeobox 1a
, ventral anterior homeobox 1