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VIPR1 encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. 再加上，我们可以发Vasoactive Intestinal Peptide Receptor 1 抗体 (126) 和 和数多这个蛋白质的别的产品。
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In vitro-polarized macrophages by GM-CSF (显示 CSF2 ELISA试剂盒) (GM-MO), with a proinflammatory profile, expressed higher levels of VIP (显示 Vip ELISA试剂盒) receptors, vasoactive intestinal polypeptide (显示 Vip ELISA试剂盒) receptors 1 and 2 (VPAC1 and VPAC2 (显示 VIPR2 ELISA试剂盒), respectively), than macrophages polarized by M-CSF (显示 CSF1 ELISA试剂盒) (M-MO) with anti-inflammatory activities. RA synovial macrophages, according to their GM-CSF (显示 CSF2 ELISA试剂盒)-like polarization state, expressed both VPAC1 and VPAC2 (显示 VIPR2 ELISA试剂盒).
VPAC1 rs9677 CC genotype could be correlated with a reduced response to statin therapy and seems to be involved in diabetes cardiomyopathy in female patients with type 2 diabetes.
The results reveal that more severe inflammation, based on high levels of IL-6 (显示 IL6 ELISA试剂盒), is associated with lower expression of VPAC1 and, conversely, with increased expression of VPAC2 (显示 VIPR2 ELISA试剂盒).
variations at the 3'UTR (显示 UTS2R ELISA试剂盒) of the VPAC-1 gene act synergistically to affect the expression of the luciferase as well as of the GFP reporter genes expressed in HEK293T cells.
These data suggest that VPAC1 overexpression is associated with poorer differentiation of colon cancer, which is likely caused by subsequent EGFR (显示 EGFR ELISA试剂盒) activation in cancer cells.
VIP (显示 Vip ELISA试剂盒) regulates CFTR (显示 CFTR ELISA试剂盒) membrane expression and function in Calu (显示 CALU ELISA试剂盒)-3 cells by increasing its interaction with NHERF1 and P-ERM in a VPAC1- and PKCepsilon (显示 PRKCE ELISA试剂盒)-dependent manner.
VPAC1 receptor has a role in endotoxemia in peripheral blood mononuclear cells
The overexpression of VPAC1 and VPAC2 (显示 VIPR2 ELISA试剂盒) receptors and COX-2 (显示 COX2 ELISA试剂盒) in cancer tissue gives them a potential role as targets for diagnosis of prostate cancer.
hree residues play an important role in VPAC1 interaction with the first histidine residue of VIP (显示 Vip ELISA试剂盒). These data demonstrate that VIP (显示 Vip ELISA试剂盒) and PG97-269 bind to distinct domains of VPAC1
The genetic association reported here indicates that VIP (显示 Vip ELISA试剂盒)/VPAC1 signaling can be a relevant pathway in the pathogenesis of type 2 diabetes in females
This study demonstrated that VPAC1 receptor (Vipr1)-deficient mice exhibit ameliorated experimental autoimmune encephalomyelitis, with specific deficits in the effector stage.
VPAC1R mRNA expression was significantly decreased 3 days after ischemia induced by bilateral common carotid artery occlusion
Cyclophosphamide-induced cystitis decreased VPAC1 receptor transcript expression in the urothelium of WT (4 h, 48 h, & chronic) & NGF (显示 NGFB ELISA试剂盒)-OE mice.
Data support the notion that both VPAC1 and VPAC2 (显示 VIPR2 ELISA试剂盒) receptors are dynamically regulated by Ikaros (显示 IKZF1 ELISA试剂盒), a master transcriptional regulator for thymocyte differentiation, during early thymic development.
results support that decline in VIP (显示 Vip ELISA试剂盒)/VPAC local levels may influence survival/apoptosis intracellular set point in NOD acinar cells and their clearance, contributing to gland homeostasis loss in a model of Sjogren's syndrome
Homozygous deletion of VPAC1 resulted in fetal, neonatal, and postweaning death owing to failure to thrive, intestinal obstruction, and hypoglycemia.
VIP (显示 Vip ELISA试剂盒) enhancement of the severity of dextran sodium sulfate-induced colitis is mediated solely by VPAC1 receptors in mice.
Data describe PACAP (显示 ADCYAP1 ELISA试剂盒), vasoactive intestinal polypeptide (显示 Vip ELISA试剂盒), and PAC1 (显示 ADCYAP1R1 ELISA试剂盒), VPAC1, VPAC2 (显示 VIPR2 ELISA试剂盒) transcripts or protein expression in urothelium and detrusor smooth muscle and lumbosacral dorsal root ganglia in NGF (显示 NGFB ELISA试剂盒)-overexpressing and wildtype mice.
VPAC(1)-R activation aggravates atherosclerotic lesion formation in apolipoprotein E (显示 APOE ELISA试剂盒)-deficient mice through enhanced inflammatory activity in the vessel wall.
VIP (显示 Vip ELISA试剂盒) and its receptors (VPAC1, VPAC2 (显示 VIPR2 ELISA试剂盒)) were identified in type II taste cells of the taste bud, and VIP (显示 Vip ELISA试剂盒) knockout mice exhibit enhanced taste preference to sweet tastants.
Implanting vascular bundles into the tissue engineered bone can significantly improve the expression levels of NK1R (显示 TACR1 ELISA试剂盒) and VIPR1.
The study confirmed the presence of VPAC1 receptor in the tissues of the porcine female reproductive tract what clearly shows the possibility of influence of vasoactive intestinal polypeptide (显示 Vip ELISA试剂盒) on the porcine ovary, oviduct and uterus.
This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. Several transcript variants encoding different isoforms have been found for this gene.
PACAP type II receptor
, VIP and PACAP receptor 1
, VIP receptor, type I
, pituitary adenylate cyclase activating polypeptide receptor, type II
, vasoactive intestinal polypeptide receptor 1
, VIP receptor subtype 1
, pituitary adenylate cyclase-activating polypeptide type II receptor
, Vasopressive intestinal peptide receptor
, vasoactive intestinal peptide receptor 1
, vasoactive intestinal polypeptide receptor 1-like
, vasoactive intestinal peptide/pituitary adenylate cyclase activating polypeptide receptor 1
, vpac1 receptor
, vasoactive intestinal polypeptide receptor type 1
, VIP receptor
, Vasoactive intestinal polypeptide receptor